A Phase III Study of SM-13496 (Lurasidone HCl) in Patients With Schizophrenia

NCT ID: NCT01614899

Last Updated: 2022-04-12

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

457 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-07-02

Study Completion Date

2014-11-17

Brief Summary

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The study evaluates the efficacy and safety of SM-13496 compared with placebo in patients with schizophrenia.

Detailed Description

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Conditions

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Schizophrenia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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SM-13496 40mg

Group Type EXPERIMENTAL

SM-13496 40mg

Intervention Type DRUG

once daily orally

SM-13496 80mg

Group Type EXPERIMENTAL

SM-13496 80mg

Intervention Type DRUG

once daily orally

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

once daily orally

Interventions

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SM-13496 40mg

once daily orally

Intervention Type DRUG

SM-13496 80mg

once daily orally

Intervention Type DRUG

Placebo

once daily orally

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patient meets DSM-IV-TR criteria for schizophrenia.
* Patient is aged 18 through 74 years at informed consent.
* Patient understands the objectives, procedures, and possible benefits and risks of the study and who provide written voluntarily consent to participate in the study

Exclusion Criteria

* Patient has a history of neuroleptic malignant syndrome, water intoxication, or paralytic ileus.
* Patient has Parkinson's disease.
* Patient has a history or complication of malignancy.
Minimum Eligible Age

18 Years

Maximum Eligible Age

74 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sumitomo Pharma Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Development Drug development Division

Role: STUDY_DIRECTOR

Sumitomo Pharma Co., Ltd.

Locations

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69 Sites

Tokyo, Etc, , Japan

Site Status

10 Sites

Kuala Lumpur, Etc, , Malaysia

Site Status

22 Sites

Seoul, Etc, , South Korea

Site Status

14 Sites

Taipei, Etc, , Taiwan

Site Status

Countries

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Japan Malaysia South Korea Taiwan

Other Identifiers

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JapicCTI-121859

Identifier Type: REGISTRY

Identifier Source: secondary_id

D1001056

Identifier Type: -

Identifier Source: org_study_id

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