The Differential Pattern of Deposition of Nano Particles in the Airways of Exposed Workers

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-05-31

Study Completion Date

2013-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Investigation of the differences between the levels of extracellular and intracellular nano-particles in workers exposed to environmental particles during their employment to enhance understanding the process of penetration of the particles to respiratory epithelial cells.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Analysis of Induced Sputum and Lung Biopsies by SEM: a Tool to Identify Source of Exposure of Workers to Hazardous Dust

NCT00511251

Occupational Exposed Population

COMPLETED

Exposure of Taxi Drivers to Ultrafine Particles and Black Carbon Within Their Vehicles

NCT03839537

Pulmonary Ventilation

COMPLETED NA

Airway Inflammation Among Workers in the Silicon Carbide Processing Industry

NCT01337180

Obstructive Lung Disease Inflammation

WITHDRAWN

Nanoparticles Emitted by Aircraft Engines, Impact on the Respiratory Function:

NCT02872727

Air France Company's Employees Working in the Marseilles and Paris Airports (Flightline and Administrative Employees)

TERMINATED

Nanoparticles Emitted by Aircraft Engines, Impact on Respiratory Function

NCT03098784

Respiratory Function

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This study investigates the following questions:

Does occupational exposure to nanoparticles influence permeation of such particles to respiratory airways? Is there a correlation between the levels of nanoparticles in sample biological fluids of the patients and their pulmonary functions.

Is there a correlation between the levels of nanoparticles in sample biological fluids of the patients and respiratory tract infections.

The study protocol includes the following steps:

Initial interview of the patient Measurement of nanoparticles in samples of exhaled breath condensate using NanoSight LM 20 Measurement of nanoparticles in induced sputum. And finally examination of the relationship between the measured parameters and the indices of pulmonary infection, and pulmonary function as measured by the pulmonary department of the TASMC.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Inadequate or Impaired Respiratory Function

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Nanoparticle exposed

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adults over 20 years of age who visit Ichilov Hospital for medical complaints/inquiries regarding respiratory tract.
* Study population is composed of people who are exposed to environmental particles form industrial sources.
* Informed consent is requested from each subject.