The Effects of Dexmedetomidine and Tracheal Intubation on Heart Rate Variability and QTc Interval
NCT ID: NCT01584570
Last Updated: 2019-02-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
80 participants
INTERVENTIONAL
2012-01-01
2013-12-23
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Control
fentanyl 1 mcg/kg before induction
0.5 mcg/kg IV infusion for 10 min, 1.0 mcg/kg IV infusion for 10 min
ECG monitoring for evaluation of QTc interval
D 0.5 group
Dexmedetomidine 0.5 ug/kg + Propofol + Sevoflurane+ Vecuronium
0.5 mcg/kg IV infusion for 10 min, 1.0 mcg/kg IV infusion for 10 min
ECG monitoring for evaluation of QTc interval
D 1.0 group
Dexmedetomidine 1.0 ug/kg + Propofol + Sevoflurane+ Vecuronium
0.5 mcg/kg IV infusion for 10 min, 1.0 mcg/kg IV infusion for 10 min
ECG monitoring for evaluation of QTc interval
Interventions
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0.5 mcg/kg IV infusion for 10 min, 1.0 mcg/kg IV infusion for 10 min
ECG monitoring for evaluation of QTc interval
Eligibility Criteria
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Inclusion Criteria
* age 20 to 60
* patient scheduled for Intubation for surgery
Exclusion Criteria
* arrythmia
* Patient who is taking a medicine which effects QTc interval
* HTN
* DM
* renal disease
* hepatic disease
* pregnant
* illiterate
20 Years
60 Years
ALL
No
Sponsors
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Yonsei University
OTHER
Responsible Party
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Locations
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Severance hospital
Seoul, , South Korea
Countries
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Other Identifiers
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4-2011-0791
Identifier Type: -
Identifier Source: org_study_id
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