Improvement of Needle Visibility in Ultrasound Guided Regional Anaesthesia

NCT ID: NCT01583010

Last Updated: 2012-04-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-12-31

Study Completion Date

2012-05-31

Brief Summary

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Needle tip visualization, although fundamental to the safety and efficacy of ultrasound-guided regional anesthesia (UGRA), can be extremely challenging. This problem is most marked at steep insertion angles. Studies in patients with UGRA demonstrate that echogenic needle designs have the potential to offer improved visibility and accuracy.

Our study pursues another approach. We use (for differentiation) echogenic nerve block needles with ANV®, a new SonoSite software-upgrade (Advanced Needle Visualization Technology®). We will compare UGRA with ANV® against standard UGRA without using this SonoSite software-upgrade. Patients undergoing femoral, supraclavicular or other nerve blocks as part of their routine anesthetic management are included.

This work represents the first randomized controlled double blinded clinical trial of ANV® in patients undergoing UGRA. We hypothesize, that we can decrease the time without needle visualization (Loss of needle time in percentage of procedure time) during in-line regional anaesthesia. Furthermore we will record quality of visibility, duration of procedure and insertion angle of the needle.

Detailed Description

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Patients scheduled to undergo surgery with femoral (n = 50) and supraclavicular (n=50) anaesthesia (100 blocks total) gets included in this study. These 50 patients will be randomized equally using sealed opaque envelopes to two parallel groups: standard treatment UGRA (n=25) and SonoSites ANV® (n= 25) UGRA.

An experienced anaesthesiologist from department of anaesthesiology, general intensive care and pain medicine will perform UGRA. Because of safety reasons and best assessment of needle visibility all UGRA in this study are going to performed with in-plane ultrasound technique. Needle length and gauge are standardized.

The ultrasound imaging of each nerve block gets recorded onto a DVD for analysis. Recording of performed UGRA will start with placement of ultrasound probe and will finish with needle leaving the skin (procedure time), get stored, checked to exclude technical failures and analysed with a one second discrimination by two blinded observers for needle visibility. All information indicating ANV®-status on ultrasound image will be deleted. Hence for procedure and following analysis we will ensure that patient and the objective observer are blinded.

Images with full needle visibility will be related to images without needle visibility. Time of needle visibility will be described in percent of procedure time.

Enduring visualization of complete needle in ultrasound beam won't be given during the whole procedure. For differentiation of complete needle visibility, partial or no visibility in in-plane UGRA, we will use needles with ultrasound visible marks (echogenic needles). If the objective observers will visualize all 3 marks and pole of the needle in ultrasound-image, needle is completely in-plane and visible for analysis. For partial visibility of marks we will use a needle visibility grading dependent to number of visible marks (One mark = poor visibility, two marks = middle visibility, three marks=good visibility). If there won't be visible marks in ultrasound image, needle is in absence and gets evaluated as "not visible".

Dependent to position of anatomic target structure each nerve block will need a different angle of needle insertion. This measured angle will be used to compare times of needle visibility dependent to insertion angle of the needle. Significant differences may appear especially in steep angles of needle.

In this study we will use Naropin® (Ropivaciane, 7.5mg/ml) as local anaesthetic for all UGRA.

Conditions

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Anaesthesia Trauma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Standard Treatment Group

Patients receiving ultrasound guided regional anaesthesia without using Advanced Needle Visualization Technology(R)

Group Type NO_INTERVENTION

No interventions assigned to this group

ANV ® Group

Patients receiving ultrasound guided regional anaesthesia with using Advanced Needle Visualization Technology(R)

Group Type ACTIVE_COMPARATOR

ANV(R)

Intervention Type DEVICE

Device: Advanced Needle Visualization Technology ®

Software update for SonoSites M-Turbo® and S-series™ ultrasound systems with enhanced 15-20Mhz ultrasound probe.

Arms: ANV ® Group

Interventions

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ANV(R)

Device: Advanced Needle Visualization Technology ®

Software update for SonoSites M-Turbo® and S-series™ ultrasound systems with enhanced 15-20Mhz ultrasound probe.

Arms: ANV ® Group

Intervention Type DEVICE

Other Intervention Names

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SonoSite M-Turbo Mbe

Eligibility Criteria

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Inclusion Criteria

* Patients, who give consent and undergo a femoral or supraclavicular nerve block.

Exclusion Criteria

* Patients get excluded if they refused or are unable to give consent by other reasons
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Vienna

OTHER

Sponsor Role lead

Responsible Party

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Reinhard Hahn

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Reinhard Hahn, Univ. Lektor Dr.

Role: PRINCIPAL_INVESTIGATOR

Medical University of Vienna

Locations

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Department of Anesthesia, Intensive Care Medicine and Pain Therapy, Medical University Vienna

Vienna, Vienna, Austria

Site Status RECRUITING

Countries

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Austria

Central Contacts

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Reinhard Hahn, Univ. Lektor Dr.

Role: CONTACT

+431404004100

Facility Contacts

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Reinhard Hahn, Univ. Lektor Dr.

Role: primary

+431404004100

Kettner Stephan, Prof. Dr.

Role: backup

+431404004100

References

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Hebard S, Hocking G. Echogenic technology can improve needle visibility during ultrasound-guided regional anesthesia. Reg Anesth Pain Med. 2011 Mar-Apr;36(2):185-9. doi: 10.1097/aap.0b013e31820d4349.

Reference Type BACKGROUND
PMID: 21425515 (View on PubMed)

Maecken T, Zenz M, Grau T. Ultrasound characteristics of needles for regional anesthesia. Reg Anesth Pain Med. 2007 Sep-Oct;32(5):440-7. doi: 10.1016/j.rapm.2007.07.002.

Reference Type BACKGROUND
PMID: 17961844 (View on PubMed)

Chapman GA, Johnson D, Bodenham AR. Visualisation of needle position using ultrasonography. Anaesthesia. 2006 Feb;61(2):148-58. doi: 10.1111/j.1365-2044.2005.04475.x.

Reference Type BACKGROUND
PMID: 16430568 (View on PubMed)

Chin KJ, Perlas A, Chan VW, Brull R. Needle visualization in ultrasound-guided regional anesthesia: challenges and solutions. Reg Anesth Pain Med. 2008 Nov-Dec;33(6):532-44. doi: 10.1016/j.rapm.2008.06.002.

Reference Type BACKGROUND
PMID: 19258968 (View on PubMed)

Other Identifiers

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EK572/2011

Identifier Type: -

Identifier Source: org_study_id

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