Quality of Life in Barrett's Esophagus and Gastro-Esophageal Reflux Disease
NCT ID: NCT01572974
Last Updated: 2018-01-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
89 participants
OBSERVATIONAL
2010-01-31
2017-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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No Barrett's esophagus
Subject without columnar lined esophagus
No interventions assigned to this group
Nondysplastic BE
Subject with columnar lined esophagus and absence of dysplasia
No interventions assigned to this group
Low grade dysplastic BE
subject with columnar lined esophagus and presence of low grade dysplasia
No interventions assigned to this group
High grade dysplastic BE
subject with columnar lined esophagus and presence of high grade dysplasia
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
At least one of the following:
Previous diagnosis of Barrett's esophagus Presence of GERD symptoms per patient report
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Kansas City Veteran Affairs Medical Center
FED
Midwest Biomedical Research Foundation
OTHER
Responsible Party
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PRATEEK SHARMA
Principal Investigator
Principal Investigators
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Prateek Sharma, MD
Role: PRINCIPAL_INVESTIGATOR
Kansas City VA Medical Center
Locations
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Kansas City VA Medical Center
Kansas City, Missouri, United States
Countries
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References
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Gerson LB, Ullah N, Hastie T, Triadafilopoulos G, Goldstein M. Patient-derived health state utilities for gastroesophageal reflux disease. Am J Gastroenterol. 2005 Mar;100(3):524-33. doi: 10.1111/j.1572-0241.2005.40588.x.
Crockett SD, Lippmann QK, Dellon ES, Shaheen NJ. Health-related quality of life in patients with Barrett's esophagus: a systematic review. Clin Gastroenterol Hepatol. 2009 Jun;7(6):613-23. doi: 10.1016/j.cgh.2009.02.024. Epub 2009 Mar 10.
Eloubeidi MA, Provenzale D. Health-related quality of life and severity of symptoms in patients with Barrett's esophagus and gastroesophageal reflux disease patients without Barrett's esophagus. Am J Gastroenterol. 2000 Aug;95(8):1881-7. doi: 10.1111/j.1572-0241.2000.02235.x.
Shaheen NJ, Green B, Medapalli RK, Mitchell KL, Wei JT, Schmitz SM, West LM, Brown A, Noble M, Sultan S, Provenzale D. The perception of cancer risk in patients with prevalent Barrett's esophagus enrolled in an endoscopic surveillance program. Gastroenterology. 2005 Aug;129(2):429-36. doi: 10.1016/j.gastro.2005.05.055.
Kruijshaar ME, Siersema PD, Janssens AC, Kerkhof M, Steyerberg EW, Essink-Bot ML; CYBAR Study Group. Patients with Barrett's esophagus perceive their risk of developing esophageal adenocarcinoma as low. Gastrointest Endosc. 2007 Jan;65(1):26-30. doi: 10.1016/j.gie.2006.05.030.
Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992 Jun;30(6):473-83.
Kulig M, Leodolter A, Vieth M, Schulte E, Jaspersen D, Labenz J, Lind T, Meyer-Sabellek W, Malfertheiner P, Stolte M, Willich SN. Quality of life in relation to symptoms in patients with gastro-oesophageal reflux disease-- an analysis based on the ProGERD initiative. Aliment Pharmacol Ther. 2003 Oct 15;18(8):767-76. doi: 10.1046/j.1365-2036.2003.01770.x.
Other Identifiers
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PS0056
Identifier Type: -
Identifier Source: org_study_id
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