Neuro-Music Therapy for Recent Onset Tinnitus: Evaluation of a Therapy Concept

NCT ID: NCT01566708

Last Updated: 2013-04-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-01-31

Study Completion Date

2013-09-30

Brief Summary

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To date, the pharmacological treatment options for tinnitus are unsatisfactory. For acute tinnitus drug treatments are only rated as being successful in approximately half of all cases. Therefore, the purpose of this study is to evaluate a neuro-music therapeutic approach (the "Heidelberg Model of Music Therapy") as a new treatment option for patients with recent onset tinnitus after initial medical treatment has failed.

Detailed Description

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Acute tinnitus is the phenomenon of ringing or buzzing in the ears without an external sound source that is persisting for a maximum of three month. Several pharmacological treatment options for acute tinnitus have been established. Nonetheless, after initial medical intervention, tinnitus symptoms are often persisting and leading to substantial distress.

The objective of the present study is to examine the efficacy of the "Heidelberg Model of Music Therapy" for patients with recent onset tinnitus whose tinnitus symptoms are enduring after pharmacological treatment. The "Heidelberg Model of Music Therapy" is a manualized short term music therapeutic intervention lasting for 9 consecutive 50-minutes sessions of individualized therapy. It strives for an integration of strategies to manage the psychological state and possibly restore the underlying neurophysiological reorganisation. At the basis of this music therapy concept is the notion that tinnitus is experienced as an auditory percept - just as musical stimuli are experienced as auditory percepts. An outstanding feature of this treatment approach is the way in which patients actively influence their symptoms. This leads to an improved self-efficacy and a more differentiated picture of their symptomatology.

For patients with chronic subjective tinnitus the "Heidelberg Model of Music Therapy" has proven to be an efficient means to reduce tinnitus distress and loudness. Prior studies indicate that these positive results are due to the beneficial influence of the music therapy on the neuronal structures underlying tinnitus pathology.

In the present study the effects of the music therapeutic intervention on tinnitus severity and tinnitus distress for patients with acute tinnitus are evaluated on the basis of a battery of psychological tests as well as psycho-physiological measurements. A task-based functional magnetic resonance imaging (fMRI) paradigm is used to investigate alterations in neuronal networks supposed to be involved in tinnitus perception and chronification.

Conditions

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Tinnitus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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treatment group

Group Type EXPERIMENTAL

Neuro-Music Therapy immediately

Intervention Type BEHAVIORAL

20 patients are randomized to receive Neuro-Music Therapy immediately. Neuro-Music Therapy takes 5 days and comprises 9 consecutive 50-minutes sessions of individual therapy. Immediately before and after treatment extensive diagnostics are performed, including psychological assessment, functional neuroimaging and electro-physiological examinations.

waiting list group

Group Type ACTIVE_COMPARATOR

Neuro-Music Therapy after waiting time

Intervention Type BEHAVIORAL

20 Patients were randomized to receive Neuro-Music Therapy after a waiting period not exceeding 6 weeks. Within this waiting time, patients undergo exactly the same diagnostic procedure as the patients of the treatment group.

control group

Group Type ACTIVE_COMPARATOR

Music-therapeutical stress management coaching

Intervention Type BEHAVIORAL

20 non-tinnitus controls matched in age, gender and hearing ability receive a music-therapeutical stress coaching program. This intervention is based on the main treatment components of the Neuro-Music Therapy for acute tinnitus with alterations of the tinnitus specific elements. Immediately before and after this five-day coaching, controls undergo exactly the same diagnostic procedure as the patients of the treatment group.

Interventions

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Neuro-Music Therapy immediately

20 patients are randomized to receive Neuro-Music Therapy immediately. Neuro-Music Therapy takes 5 days and comprises 9 consecutive 50-minutes sessions of individual therapy. Immediately before and after treatment extensive diagnostics are performed, including psychological assessment, functional neuroimaging and electro-physiological examinations.

Intervention Type BEHAVIORAL

Neuro-Music Therapy after waiting time

20 Patients were randomized to receive Neuro-Music Therapy after a waiting period not exceeding 6 weeks. Within this waiting time, patients undergo exactly the same diagnostic procedure as the patients of the treatment group.

Intervention Type BEHAVIORAL

Music-therapeutical stress management coaching

20 non-tinnitus controls matched in age, gender and hearing ability receive a music-therapeutical stress coaching program. This intervention is based on the main treatment components of the Neuro-Music Therapy for acute tinnitus with alterations of the tinnitus specific elements. Immediately before and after this five-day coaching, controls undergo exactly the same diagnostic procedure as the patients of the treatment group.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of acute tinnitus persisting for a maximum of 3 month
* Adults, aged 18 or over
* No contraindication for MRI scan
* Initial medical intervention is accomplished
* Patients are able to understand, read and speak German fluently
* Patients are able to give written informed consent

Exclusion Criteria

* Clinical diagnosis of chronic tinnitus persisting for longer than 3 month
* Tinnitus related to anatomic lesions of the ear, to retrocochlear lesions or to cochlear implantation
* Clinical diagnosis of severe mental disorder
* Clinical diagnosis of Menière's Disease
* Severe hyperacusis
* Severe hearing impairment
* Any contraindication for MRI scan
* Initial medical intervention is not accomplished
* Patients are not able to understand, read and speak German fluently
* Patients are not able to give written informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Heidelberg University

OTHER

Sponsor Role collaborator

Clinic of Diagnostic and Interventional Neuroradiology, Saarland University Clinic, Homburg, Germany

UNKNOWN

Sponsor Role collaborator

German Center for Music Therapy Research

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hans V Bolay, Prof. Dr.

Role: STUDY_DIRECTOR

German Center for Music Therapy Research

Miriam Grapp

Role: PRINCIPAL_INVESTIGATOR

German Center for Music Therapy Research

Locations

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German Center for Music Therapy Research

Heidelberg, Baden-Wurttemberg, Germany

Site Status

Countries

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Germany

Other Identifiers

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00.181.2011

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

CMTR-TA-01

Identifier Type: -

Identifier Source: org_study_id

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