Glucose as a Mediator of Self-control Performances in Patients With Schizophrenia

NCT ID: NCT01563016

Last Updated: 2012-03-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-04-30

Study Completion Date

2013-04-30

Brief Summary

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The research aims to investigate the relationship between self-control ability and blood glucose level in schizophrenic patients. The main purpose of the present study is to explore whether the close relationship of blood glucose and self-regulatory strength observed in healthy individuals, is applicable to schizophrenic patients. More specifically, the current study aims

* to investigate whether the exertion of self-control reduces blood glucose,
* to examine whether low level of blood glucose deteriorates subsequent self-control performances
* to examine whether restoring the glucose level eliminates these impairments, in schizophrenic patients.

Detailed Description

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Conditions

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Schizophrenia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Glucose & Depleting

participants will perform in a depleting task and receive a glucose drink

Group Type EXPERIMENTAL

glucose drink

Intervention Type DIETARY_SUPPLEMENT

participants will receive a drink rich in glucose

Glucose & non-depleting

participants will perform in a non-depleting task and receive a glucose drink

Group Type PLACEBO_COMPARATOR

glucose drink

Intervention Type DIETARY_SUPPLEMENT

participants will receive a drink rich in glucose

Placebo & depleting

participants will perform in a depleting task and receive a placebo drink

Group Type NO_INTERVENTION

No interventions assigned to this group

Placebo & non depleting

participants will perform in a non depleting task and receive a placebo drink

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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glucose drink

participants will receive a drink rich in glucose

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Aged 15 or above
* DSM-IV diagnosis of schizophrenia, schizoaffective disorder, schizophreniform psychosis, brief psychosis, psychosis NOS or delusional disorder
* Cantonese-speaking Chinese
* Ability to understand the nature of the study and sign informed consent

Exclusion Criteria

* Organic Brain disorder
* Known history of intellectual disability
* Priority Follow Up (Subtarget or Target)
* All allergic to any sugar or artificial sweeteners
* Diabetics
* Physical Disability
Minimum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Queen Mary Hospital, Hong Kong

OTHER

Sponsor Role collaborator

The University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Eric YH Chen, MD

Role: PRINCIPAL_INVESTIGATOR

The University of Hong Kong

Locations

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The University of Hong Kong

Hong Kong, , China

Site Status

Countries

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China

Central Contacts

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Eric YH Chen, MD

Role: CONTACT

852-22553063

Chung-Ming Leung, Bsc

Role: CONTACT

852-64054460

Facility Contacts

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Bonnie Choi

Role: primary

Other Identifiers

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selfcontrolvsglucose

Identifier Type: -

Identifier Source: org_study_id

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