Evaluation of Patient Reported Outcome Instruments in Celiac Disease Patients

NCT ID: NCT01560169

Last Updated: 2013-10-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

110 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-03-31

Study Completion Date

2013-09-30

Brief Summary

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This is an evaluation of celiac-specific patient reported outcome instruments in celiac disease patients.

Detailed Description

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Conditions

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Celiac Disease

Keywords

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Celiac Disease Coeliac Disease Celiac Sprue Keilakia Disease

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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Gluten challenge

Gluten containing or gluten-free study food in established celiac disease patients

No interventions assigned to this group

Observation

Observation in newly diagnosed celiac disease patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* History of biopsy proven celiac disease
* Adherence to a gluten-free diet (established patients only)
* TG2 negative (established patients only)
* TG2 positive (newly diagnosed patients only)
* Signed informed consent

Exclusion Criteria

* History of IgE-mediated reactions to gluten
* Significant laboratory abnormalities
* History of untreated or GI disease
* Positive pregnancy test
* Any medical condition which could adversely affect study participation
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alvine Pharmaceuticals Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Daniel Adelman, MD

Role: STUDY_CHAIR

Alvine Pharmaceuticals Inc.

Locations

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University of California, San Diego

La Jolla, California, United States

Site Status

Kaiser Permanente Southern California, Allergy Department

San Diego, California, United States

Site Status

University of Colorado, Denver

Aurora, Colorado, United States

Site Status

University of Chicago Celiac Disease Center

Chicago, Illinois, United States

Site Status

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Site Status

Mayo Clinic

Rochester, Minnesota, United States

Site Status

Columbia University

New York, New York, United States

Site Status

Cleveland Clinic

Cleveland, Ohio, United States

Site Status

Thomas Jefferson University

Philadelphia, Pennsylvania, United States

Site Status

University of Alberta

Edmonton, Alberta, Canada

Site Status

Countries

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United States Canada

Other Identifiers

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ALV003-1121

Identifier Type: -

Identifier Source: org_study_id