A Comparison Study of the Tensile Strength of Sutures Used in Dermatologic Surgery on the Day of Suture Removal, Following Wound Care With Two Different Products

NCT ID: NCT01533675

Last Updated: 2017-05-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-05-31

Study Completion Date

2011-08-31

Brief Summary

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Sutures are an integral part of surgery and available materials are diverse, as are the options for post-procedure care. Both saline and hydrogen peroxide are commonly used cleansing agents. This study aims to compare the effect of saline and hydrogen peroxide on the tensile strength of 4-0 nylon sutures following removal from a cutaneous surgical wound.

Detailed Description

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Conditions

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Sutured Wounds

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Hydrogen peroxide

Group Type EXPERIMENTAL

Hydrogen peroxide

Intervention Type OTHER

Once daily topical application of 3% hydrogen peroxide using a cotton-tipped applicator

Saline

Group Type ACTIVE_COMPARATOR

Saline

Intervention Type OTHER

Once daily topical application of normal saline, using a cotton-tipped applicator

Interventions

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Hydrogen peroxide

Once daily topical application of 3% hydrogen peroxide using a cotton-tipped applicator

Intervention Type OTHER

Saline

Once daily topical application of normal saline, using a cotton-tipped applicator

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Subject is willing to comply with the informed consent procedures
* Subject's wound is on the body or scalp
* Subject will be able to come to the clinic for suture removal on day 14

Exclusion Criteria

* Subject is less than 18 years of age
* Subject's wound was not closed with 4-0 nylon sutures
* Subject's wound is on the face
* Subject plans to apply other topicals to the area under study
* Subject's suture is removed before or after day 14
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Miami

OTHER

Sponsor Role lead

Responsible Party

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Keyvan Nouri

Keyvan Nouri, M.D Professor of Dermatology, Ophthalmology & Otolaryngology, Chief of Dermatology Servic

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Miami Hospital and Clinics/Sylvester Comprehensive Cancer Center

Miami, Florida, United States

Site Status

Countries

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United States

References

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Snyder CC. On the history of the suture. Plast Reconstr Surg. 1976 Oct;58(4):401-6. doi: 10.1097/00006534-197610000-00001. No abstract available.

Reference Type RESULT
PMID: 785506 (View on PubMed)

Hochberg J, Meyer KM, Marion MD. Suture choice and other methods of skin closure. Surg Clin North Am. 2009 Jun;89(3):627-41. doi: 10.1016/j.suc.2009.03.001.

Reference Type RESULT
PMID: 19465201 (View on PubMed)

Other Identifiers

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# 20100301

Identifier Type: -

Identifier Source: org_study_id

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