Chlorine Dioxide Versus Saline for Wound Irrigation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

201 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-08-31

Study Completion Date

2009-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This research is being done because the investigators are trying to examine the safety and effectiveness of this wound cleaning liquid, CACD (chlorine dioxide). The investigators are trying to see if this liquid has the ability to decrease infection rates and decrease the scarring effects from the healing process. In animal studies, CACD has been shown to decrease scar formation and decrease the risk of wound infections. CACD is also used for the treatment of burns to decrease infection rates and improve wound healing. CACD is not FDA approved for this specific use, but it is FDA and USDA approved for reducing bacterial contamination on meat and food products for human consumption. In addition, an investigational drug (IND) application has been submitted to the FDA for this study. The FDA has approved the use of this solution for this study.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies

NCT05989386

Surgical Site Infection Surgical Wound Surgical Incision +5 more

RECRUITING PHASE2/PHASE3

Addition of Pre-wound Closure Povidone Iodine Wash Versus Direct Wound Closure Effect on Surgical Site Infections

NCT05077592

Surgical Site Infection Surgical Wound Infection

UNKNOWN PHASE4

Chlorhexidine Cloths to Reduce Surgical Site Infection in Cesarean Deliveries

NCT04202471

Surgical Site Infection

WITHDRAWN NA

Topical Silver for Prevention of Wound Infection After Cesarean Delivery

NCT01169064

Wound Infection

TERMINATED NA

Bacterial Contamination: Iodine vs Saline Irrigation in Pediatric Spine Surgery

NCT02527512

Surgical Site Infection

COMPLETED PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Wound - in Medical Care

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

chlorine dioxide

2 arms

Group Type EXPERIMENTAL

chlorine dioxide

Intervention Type BIOLOGICAL

one time wash with 50ppm CD solution

saline

one time wash with 50-100cc of normal saline

Group Type ACTIVE_COMPARATOR

saline

Intervention Type BIOLOGICAL

one time wash with 50-100 cc normal saline

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

chlorine dioxide

one time wash with 50ppm CD solution

Intervention Type BIOLOGICAL

saline

one time wash with 50-100 cc normal saline

Intervention Type BIOLOGICAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18-100 years old
* simple laceration requiring irrigation \& sutures
* patient has method of contact
* patient is willing to return to ED in 3-4 mths