Gastric Cancer Metastasized to the Central Nervous System (CNS)

NCT ID: NCT01456455

Last Updated: 2016-10-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-08-31

Study Completion Date

2020-08-31

Brief Summary

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Descriptive registry to investigate frequency of HER-2 positive gastric cancer involving CNS.

Exploration of additional prognostic factors for brain involvement from gastric cancer.

Detailed Description

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HER2 Status E-Cadherin Status

Conditions

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Gastric Cancer

Study Design

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Observational Model Type

COHORT

Eligibility Criteria

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Inclusion Criteria

* in order to be eligible for the study, the diagnosis of gastric cancer and/or lower esophageal cancer must be confirmed histologically. CNS involvement must be confirmed either via independent neuroradiological and/or positive CSF cytology.

Exclusion Criteria

* Patients whose diagnosis is not confirmed upon pathological review or where the CNS involvement cannot be confirmed after neuroradiological review will be excluded from this study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Zurich

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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01 Studienregister MasterAdmins

Role: STUDY_DIRECTOR

UniversitaetsSpital Zuerich

Silvia Hofer, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital Zurich, Division of Oncology

Locations

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Dept Oncology, University Hospital Zürich

Zurich, , Switzerland

Site Status

Countries

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Switzerland

References

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Feilchenfeldt J, Varga Z, Siano M, Grabsch HI, Held U, Schuknecht B, Trip A, Hamaguchi T, Gut P, Balague O, Khanfir K, Diebold J, Jochum W, Shoji H, Kushima R, Wagner D, Shimada Y, Cats A, Knuth A, Moch H, Aebi S, Hofer S. Brain metastases in gastro-oesophageal adenocarcinoma: insights into the role of the human epidermal growth factor receptor 2 (HER2). Br J Cancer. 2015 Sep 1;113(5):716-21. doi: 10.1038/bjc.2015.279. Epub 2015 Aug 27.

Reference Type RESULT
PMID: 26313663 (View on PubMed)

Other Identifiers

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UGICNS

Identifier Type: -

Identifier Source: org_study_id

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