Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or Atypical Teratoid Rhabdoid Tumor

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2011-11-01

Brief Summary

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This research trial studies biomarkers in samples from patients with rhabdoid tumor of the kidney and atypical teratoid rhabdoid tumor. Studying biomarkers of tissue samples from patients with cancer in the laboratory may help doctors learn more about changes the occur in DNA and identify biomarkers related to cancer.

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Detailed Description

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PRIMARY OBJECTIVES:

I. To determine if there are molecular differences between rhabdoid tumor of the kidney (RTK) and the atypical teratoid rhabdoid tumor (ATRT).

OUTLINE:

Archived tumor tissue samples are analyzed for gene expression profile and microRNA profile.

Conditions

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Childhood Atypical Teratoid/Rhabdoid Tumor Rhabdoid Tumor of the Kidney

Study Groups

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Ancillary-Correlative (gene expression profile, miRNA profile)

Archived tumor tissue samples are analyzed for gene expression profile and microRNA profile.

Laboratory Biomarker Analysis

Intervention Type OTHER

Correlative studies

Interventions

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Laboratory Biomarker Analysis

Correlative studies

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Samples of RTK and ATRT provided by the Children?s Oncology Group (COG)

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Simone Sredni

Role: PRINCIPAL_INVESTIGATOR

Children's Oncology Group

Locations

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Childrens Oncology Group

Philadelphia, Pennsylvania, United States

Site Status

Countries

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United States