Protein Expression in Samples From Young Patients With Rhabdomyosarcoma
NCT ID: NCT01426945
Last Updated: 2016-05-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
77 participants
OBSERVATIONAL
2011-11-30
Brief Summary
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PURPOSE: This research trial studies protein expression in samples from young patients with rhabdomyosarcoma.
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Detailed Description
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* To measure the protein expression of candidate proteins in human rhabdomyosarcoma (RMS) tumor samples.
OUTLINE: Archived tumor tissue samples are analyzed for protein expression (i.e., Notch1, Hey1, FGFR4, and Sp1) by IHC techniques and standard commercially available antibodies. Candidate proteins are then correlated with each patient age, gender, rhabdomyosarcoma (RMS) tumor stage, and RMS tumor subtype.
Conditions
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Study Design
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CASE_ONLY
RETROSPECTIVE
Interventions
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protein expression analysis
immunohistochemistry staining method
laboratory biomarker analysis
Eligibility Criteria
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Inclusion Criteria
* Tumor tissue samples from children with rhabdomyosarcoma (RMS) enrolled in the Children's Oncology Group clinical trials
* Alveolar rhabdomyosarcoma (ARMS)
* Embryonal rhabdomyosarcoma (ERMS)
PATIENT CHARACTERISTICS:
* Not specified
PRIOR CONCURRENT THERAPY:
* Not specified
ALL
No
Sponsors
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National Cancer Institute (NCI)
NIH
Children's Oncology Group
NETWORK
Responsible Party
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Principal Investigators
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Corinne M. Linardic, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Duke Cancer Institute
Other Identifiers
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COG-ARST11B3
Identifier Type: OTHER
Identifier Source: secondary_id
ARST11B3
Identifier Type: OTHER
Identifier Source: secondary_id
NCI-2011-03534
Identifier Type: REGISTRY
Identifier Source: secondary_id
ARST11B3
Identifier Type: -
Identifier Source: org_study_id
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