Registry for Pulmonary Hypertension in China

NCT ID: NCT01417338

Last Updated: 2017-06-09

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 3079 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2009-08-31
• Study Completion Date: 2020-12-31

Brief Summary

1. To characterize the demographics and clinical course of the patient population diagnosed as having WHO group I pulmonary arterial hypertension and WHO group IV pulmonary hypertension due to chronic thromboembolic pulmonary hypertension

2. To describe real-world outcome of Chinese patients with WHO group I pulmonary arterial hypertension and WHO group IV pulmonary hypertension due to chronic thromboembolic pulmonary hypertension

3. To evaluate differences in patient outcomes according to classification subgroup

4. To identify clinical predictors of long-term survival

5. To assess the relationship between targeted therapies for pulmonary arterial hypertension and patient outcomes

Detailed Description

Data describing the natural history of idiopathic and familial pulmonary arterial hypertension were derived from a registry conducted at our institution prior to 2006. Since then, targeted therapies for pulmonary arterial hypertension have been introduced in China. It is probably that the prognosis of Chinese patients with WHO group I pulmonary arterial hypertension and WHO group IV pulmonary hypertension due to chronic thromboembolic pulmonary hypertension has also been improved as western countries. Therefore, the aim of the present study was to describe real-world outcome of Chinese patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension and identify factors that may predict outcome. Our study will provide an updated picture of the clinical course of a more broadly defined scope of pulmonary hypertension and the effects of current therapy on survival, enabling the collection of data on demographics, clinical course, treatments, and outcomes.

Conditions

Pulmonary Arterial Hypertension; Chronic Thromboembolic Pulmonary Hypertension; Death

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Pulmonary hypertension group

Patients who were firstly diagnosed as pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Signed patients'consent
• Diagnosed by right heart catheterization one month within study enrollment
• patients who were firstly diagnosed as pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Chinese Academy of Medical Sciences, Fuwai Hospital

OTHER

Sponsor Role: lead

Responsible Party

Jianguo He

Director of Pulmonary vascular disease center

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Jian-Guo He, M.D.

Role: PRINCIPAL_INVESTIGATOR

Fu Wai Hospital

Locations

Fu Wai Hospital

Beijing, , China

Site Status: RECRUITING

Countries

China

Central Contacts

Jian-Guo He, M.D.

Role: CONTACT

hejianguofw@gmail.com

86-10-88398060

Facility Contacts

Jian-Guo He, M.D. & Ph.D

Role: primary

hejianguofw@gmail.com

86-10-88398060

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Other Identifiers

CIFuwaiHospital

Identifier Type: -

Identifier Source: org_study_id