Pulmonary Vasculature and Right Heart Dysfunction in Chronic Obstructive Pulmonay Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-06-15

Study Completion Date

2020-12-31

Brief Summary

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The pulmonary vasculopathy and right heart dysfunction in COPD are drawing increasing attention these days. Recent researches show that pulmonary vasculopathy and right heart dysfunction relate to greater severity in COPD. Applying appropriate modalities for early detection of pulmonary vasculopathy and right heart dysfunction is of great importance. What's more, the interaction mechanism between pulmonary vasculature, right heart and COPD still needs to be further studied. The aim of our study is to develop an assessment system of pulmonary vasculopathy and right heart dysfunction in COPD patients and elucidate their impact on COPD course and outcome.

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Detailed Description

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Conditions

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COPD Pulmonary Vascular Disorder Right Ventricular Dysfunction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* stable COPD patients

Exclusion Criteria

* patents with other respiratory diseases and pulmonary hypertension other than group 3 PH;
* psychopath, addict or patients not able to coordinate;
* patients in pregnancy or breastfeeding;
* patients with limited life expectancy;
* patients with contraindiction for MRI or PET;
* patients having cerebrovascular events in 3 months;
* unstable COPD patients

Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes