Registry for Chronic Obstructive Pulmonary Disease With Sleep Apnea Hypopnea Syndrome in China

NCT ID: NCT03182309

Last Updated: 2017-06-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

3502 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-06-15

Study Completion Date

2020-12-31

Brief Summary

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COPD and sleep apnea dyspnea syndrome represent two of the most common chronic lung diseases. It is reported that the prevalence of COPD with sleep apnea dyspnea syndrome is also very high. COPD and sleep apnea may have pathological or genetics interactions so that patients having both disorders tend to have worse outcomes than either condition alone. Data reflecting the prevalence, disease course and outcome of overlap syndrome is very limited in China. Therefore, the aim of the study is to describe the prevalence, treatment and outcome in Chinese patients and exploring the underlying interaction mechanism.

Detailed Description

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Conditions

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COPD Sleep Apnea Syndromes

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* COPD patients with informed consent

Exclusion Criteria

* pregnant patients, patients with serious respiratory diseases other than COPD, patients with limited life expectancy, patients that can't coordinate well
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chinese Academy of Medical Sciences, Fuwai Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jianguo He

Chief of Pulmonary Vascular Disease Center

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Renmin Hospital of Wuhan University

Wuhan, Hubei, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Ke Hu, MD

Role: CONTACT

18971035988

Facility Contacts

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Ke Hu, MD

Role: primary

18971035988

References

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Zhao Z, Zhang D, Sun H, Chang D, Lv X, Lin J, Liu J, Wu X, Hu K, Guo X, Tong Z. Anxiety and depression in patients with chronic obstructive pulmonary disease and obstructive sleep apnea: the overlap syndrome. Sleep Breath. 2022 Dec;26(4):1603-1611. doi: 10.1007/s11325-021-02500-2. Epub 2021 Nov 16.

Reference Type DERIVED
PMID: 34783978 (View on PubMed)

Zhu J, Zhao Z, Wu B, Shi Z, Nie Q, Fu Z, Zeng Z, Hu W, Dong M, Xiong M, Hu K. Effect of Body Mass Index on Lung Function in Chinese Patients with Chronic Obstructive Pulmonary Disease: A Multicenter Cross-Sectional Study. Int J Chron Obstruct Pulmon Dis. 2020 Oct 13;15:2477-2486. doi: 10.2147/COPD.S265676. eCollection 2020.

Reference Type DERIVED
PMID: 33116464 (View on PubMed)

Hu W, Dong M, Xiong M, Zhao D, Zhao Y, Wang M, Wang T, Liu Z, Lu L, Hu K. Clinical Courses and Outcomes of Patients with Chronic Obstructive Pulmonary Disease During the COVID-19 Epidemic in Hubei, China. Int J Chron Obstruct Pulmon Dis. 2020 Sep 23;15:2237-2248. doi: 10.2147/COPD.S265004. eCollection 2020.

Reference Type DERIVED
PMID: 33061341 (View on PubMed)

Zhu J, Zhao Z, Nie Q, Wang Y, Fu Z, Guo X, Hu K. Effect of lung function on the apnea-hypopnea index in patients with overlap syndrome: a multicenter cross-sectional study. Sleep Breath. 2020 Sep;24(3):1059-1066. doi: 10.1007/s11325-019-01961-w. Epub 2019 Nov 25.

Reference Type DERIVED
PMID: 31768930 (View on PubMed)

Other Identifiers

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2016YFC1304403

Identifier Type: -

Identifier Source: org_study_id

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