Protein Expression in Human Neuroblastoma Tumor Samples
NCT ID: NCT01407731
Last Updated: 2016-05-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
20 participants
OBSERVATIONAL
2011-07-31
2016-05-31
Brief Summary
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PURPOSE: This laboratory studying is looking at protein expression in tumor tissue samples from patients with neuroblastoma.
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Detailed Description
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* To determine whether intersectin (ITSN1) proteins are present at elevated levels in primary human tumor samples.
OUTLINE: Archived tumor tissue samples are analyzed for intersectin (ITSN1) expression by western blot assays with enhanced chemiluminescence and exposed to X-ray film. The films are scanned, and levels of ITSN1 signal are quantified by densitometry.
Conditions
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Study Design
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CASE_ONLY
RETROSPECTIVE
Interventions
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protein expression analysis
western blotting
laboratory biomarker analysis
Eligibility Criteria
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Inclusion Criteria
* Diagnosed with neuroblastoma
* Banked primary tumor samples from patients with stage 1, 2, 3, and 4 disease
PATIENT CHARACTERISTICS:
* Not specified
PRIOR CONCURRENT THERAPY:
* Not specified
ALL
No
Sponsors
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National Cancer Institute (NCI)
NIH
Children's Oncology Group
NETWORK
Responsible Party
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Principal Investigators
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John P. O'Bryan, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Illinois at Chicago
Other Identifiers
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COG-ANBL11B4
Identifier Type: OTHER
Identifier Source: secondary_id
ANBL11B4
Identifier Type: OTHER
Identifier Source: secondary_id
NCI-2011-03799
Identifier Type: REGISTRY
Identifier Source: secondary_id
ANBL11B4
Identifier Type: -
Identifier Source: org_study_id
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