Comparison of the Glidescope and Macintosh Laryngoscope for Double Lumen Endotracheal Tube Intubation

NCT ID: NCT01404780

Last Updated: 2013-02-22

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 70 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2011-06-30
• Study Completion Date: 2013-02-28

Brief Summary

Patients undergoing chest surgery often require insertion of a breathing tube (double lumen tube) after they are unconscious. The double lumen tube enables the anaesthetist to ventilate (assist breathing) one lung at a time. The other lung is partially deflated to enable enough space for the surgeon to perform the procedure. The breathing tube is inserted with a laryngoscope (blade with a light at the end) so the vocal cords can be seen. This is standard medical practise. Two laryngoscopes are commonly used at Toronto General Hospital to insert the tube. The Macintosh laryngoscope has been is use for over 50 years and the Glidescope for over 10 years. Both devices have been extensively researched for single lumen tubes insertion and found to be very safe and effective. Research is limited to say which of the two laryngoscope is the most effective for double lumen tubes.

Detailed Description

The Glidescope (GVL) has been extensively studied for single lumen tube intubation and found to be a very safe and useful device. It is a particularly useful for patients with difficult airways as it has a camera attached to the blade. Despite being used for double lumen tube (DLT) intubations, research of its effectiveness and safety, is lacking. The study aims to determine the speed and safety of the GVL for DLT insertion. This information will assist anaesthetists in choosing the appropriate laryngoscope for DLT intubation of their patients.

Conditions

Lung Disease

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: NONE

Study Groups

The GlideScope (GVL)

Group Type: EXPERIMENTAL

GlideScope (GVL)

Intervention Type: DEVICE

The Glidescope (GVL) has not been extensively studied for double lumen tube intubation. The GVL may be particularly useful for patients with difficult airways as it has a camera attached to the blade.

Macintosh direct laryngoscope (MDL)

Group Type: ACTIVE_COMPARATOR

Macintosh Direct Laryngoscope (MDL)

Intervention Type: DEVICE

Current standard of care at UHN for 50 years

Interventions

GlideScope (GVL)

The Glidescope (GVL) has not been extensively studied for double lumen tube intubation. The GVL may be particularly useful for patients with difficult airways as it has a camera attached to the blade.

Intervention Type: DEVICE

Macintosh Direct Laryngoscope (MDL)

Current standard of care at UHN for 50 years

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

Population: planned elective lung surgery requiring general anaesthesia with a double lumen endotracheal intubation, signed informed patient consent.

Exclusion Criteria

• Previous failed intubation,
• history of difficult intubation or anticipated difficult intubation (2 risk factors of mallampati score 3 or greater,
• incisor gap < 3.5cm, thyromental distance < 6.5cm,
• reduced neck extension and flexion),
• alternative method of intubation indicated eg rapid sequence intubation,
• fibreoptic intubation,
• contra-indication to a left double lumen tube eg endobronchial tumor,
• significant deviation or compression of the trachea and bronchi.,
• contraindication to one lung ventilation eg severe hypoxia or pulmonary hypertension,
• anticipated difficult bag mask ventilation,
• symptomatic gastro-oesophageal reflux,
• oral/pharyngeal/laryngeal carcinoma,
• loose teeth,
• allergy to rocuronium, BMI > 40.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Health Network, Toronto

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Adriaan Van Rensburg, MD

Role: PRINCIPAL_INVESTIGATOR

University Health Network, Toronto General Hospital

Locations

Toronto General Hospital

Toronto, Ontario, Canada

Countries

Canada

Other Identifiers

11-0270-B

Identifier Type: -

Identifier Source: org_study_id