Early Diagnosis of Pulmonary Hypertension in Patients With Inflammatory Rheumatic Connective Tissue Diseases
NCT ID: NCT01387035
Last Updated: 2022-07-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
50 participants
OBSERVATIONAL
2010-01-31
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* men and women\> 18 years
* fulfill the current definition of a collagen vascular disease according to the actual guidelines of the American College of Rheumatology (ACR)
Exclusion Criteria
* significant restriction of the left ventricle, unstable coronary artery disease and myocardial infarction in the last 6 months
* patients with other lung diseases (as the pulmonary infestations as part of systemic disease) or related musculoskeletal disorders influencing baseline exercise capacity
* pregnancy
18 Years
ALL
No
Sponsors
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Heidelberg University
OTHER
Responsible Party
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Prof. Dr. med. Ekkehard Gruenig
Prof. Dr. med. Ekkehard Grünig
Principal Investigators
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Christian Nagel, MD
Role: STUDY_DIRECTOR
Center for pulmonary hypertension, Thoraxclinic Heidelberg
Ekkehard Grünig, Professor
Role: STUDY_DIRECTOR
Center for pulmonary hypertension, Thoraxclinic Heidelberg
Locations
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Center for pulmonary Hypertension, Thoraxclinic Heidelberg
Heidelberg, , Germany
Countries
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Central Contacts
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Facility Contacts
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References
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Nagel C, Marra AM, Benjamin N, Blank N, Cittadini A, Coghlan G, Distler O, Denton CP, Egenlauf B, Fiehn C, Fischer C, Harutyunova S, Hoeper MM, Lorenz HM, Xanthouli P, Bossone E, Grunig E. Reduced Right Ventricular Output Reserve in Patients With Systemic Sclerosis and Mildly Elevated Pulmonary Artery Pressure. Arthritis Rheumatol. 2019 May;71(5):805-816. doi: 10.1002/art.40814. Epub 2019 Apr 10.
Nagel C, Henn P, Ehlken N, D'Andrea A, Blank N, Bossone E, Bottger A, Fiehn C, Fischer C, Lorenz HM, Stockl F, Grunig E, Egenlauf B. Stress Doppler echocardiography for early detection of systemic sclerosis-associated pulmonary arterial hypertension. Arthritis Res Ther. 2015 Jun 19;17(1):165. doi: 10.1186/s13075-015-0673-7.
Other Identifiers
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S-360/2009
Identifier Type: -
Identifier Source: org_study_id
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