The Effect of Metformin on the Correlation Between Hyperinsulinemia and Hypertension

NCT ID: NCT01342614

Last Updated: 2011-05-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

140 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-05-31

Study Completion Date

2009-08-31

Brief Summary

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The objective of this study is to investigate the effect of metformin on the correlation between hyperinsulinemia and hypertension.

Detailed Description

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Conditions

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Diabetes Mellitus Essential Hypertension

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Fosinopril group

Fosinopril group received fosinopril, 10mg, once per day.

Group Type ACTIVE_COMPARATOR

Fosinopril

Intervention Type DRUG

Fosinopril group received fosinopril, 10mg, once per day.

Metformin group

Metformin group was treated with metformin hydrochloride, 500mg, three times per day

Group Type EXPERIMENTAL

Metformin

Intervention Type DRUG

Metformin group was treated with metformin hydrochloride, 500mg, three times per day

Interventions

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Fosinopril

Fosinopril group received fosinopril, 10mg, once per day.

Intervention Type DRUG

Metformin

Metformin group was treated with metformin hydrochloride, 500mg, three times per day

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* 20 to 65 years of age, regardless of sex
* duration of hypertension was \<5 years
* overweight or obesity, mild to moderate hypertension, receive no euglycemic agent or antiobesity drug
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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China-Japan Friendship Hospital

OTHER

Sponsor Role lead

Responsible Party

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China-Japan Friendship Hospital

Other Identifiers

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MET140

Identifier Type: -

Identifier Source: org_study_id

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