PHARMO Institute Seroquel Safety Study

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

18325 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-09-30

Study Completion Date

2010-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this observational study is to study specific outcomes of interest in users of quetiapine compared with all other atypical antipsychotics and specifically olanzapine and risperidone. The outcomes of interest are all-cause mortality, failed suicide attempts, extrapyramidal symptoms, diabetes mellitus, hypothyroidism, acute myocardial infarction and stroke. This retrospective cohort study is based on population-based record linkage system (PHARMO RLS) capturing about 2.5 millions residents in the Netherlands.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Seroquel in Bipolar Depression Versus Lithium

NCT00206141

Bipolar Disorder Bipolar Depression Depression

COMPLETED PHASE3

General Practice Research Database Seroquel XR Safety Study

NCT01447082

Schizophrenia Major Depressive Disorder Bipolar Disorder

COMPLETED

Seroquel (Quetiapine Fumarate) InPractice Evaluation Programme

NCT00921362

Schizophrenia

COMPLETED

Efficacy and Safety of Seroquel Plus Mood Stabilizer in the Maintenance of Bipolar I Disorder

NCT00081380

Bipolar Disorder

COMPLETED PHASE3

Efficacy & Safety of Seroquel Plus Mood Stabilizer in the Maintenance of Bipolar I Disorder

NCT00107731

Bipolar I Disorder

COMPLETED PHASE3

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Schizophrenia Major Depressive Disorder Bipolar Disorder Generalized Anxiety Disorder

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Quetiapine

Quetipine users

No interventions assigned to this group

All other atypical antipsychotics

All other atypical antipsychotics users

No interventions assigned to this group

Risperidone

Risperidone users

No interventions assigned to this group

Olanzapine

Olanzapine users

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Episode of new use of atypical antipsychotics in naïve (not used antipsychotic drugs for a year) users of antipsychotics.

Exclusion Criteria

* less than a year of recorded history before the cohort entry date
* use of multiple antipsychotics concomitantly
* duration and dose of the antipsychotic drug cannot be determined

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No