A Comparative Study of Knee Systems

NCT ID: NCT01331278

Last Updated: 2011-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-09-30

Study Completion Date

2011-03-31

Brief Summary

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The custom cutting guides personalized for each patient via pre-operative MRI will result in significantly faster intraoperative time with comparable knee alignment accuracy, cost, knee function, and patient satisfaction.

Detailed Description

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Conditions

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Osteoarthritis of the Knee

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Custom Cutting Blocks

Group Type ACTIVE_COMPARATOR

Total Knee Arthroplasty with Custom Cutting Blocks

Intervention Type PROCEDURE

Subjects randomized to this study group will undergo TKA with patient specific custom cutting blocks generated by pre-op MRI and a Biomet Vanguard knee implant

Computer Assisted Surgery

Group Type ACTIVE_COMPARATOR

Total Knee Arthroplasty via Computer Assisted Surgery

Intervention Type PROCEDURE

Subjects randomized to this study group will receive TKA via computer assisted surgery and a Biomet Vanguard knee implant

Interventions

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Total Knee Arthroplasty with Custom Cutting Blocks

Subjects randomized to this study group will undergo TKA with patient specific custom cutting blocks generated by pre-op MRI and a Biomet Vanguard knee implant

Intervention Type PROCEDURE

Total Knee Arthroplasty via Computer Assisted Surgery

Subjects randomized to this study group will receive TKA via computer assisted surgery and a Biomet Vanguard knee implant

Intervention Type PROCEDURE

Other Intervention Names

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Signature Knee System

Eligibility Criteria

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Inclusion Criteria

* must be scheduled to undergo TKA with no bilateral TKA planned within 6 weeks of the initial surgery date
* must be 18 years of age or older
* must be capable and willing to provide informed consent
* must have flexion contracture less than 15 degrees.
* must have ligament stability no more than 2 degrees instability in varus/valgus extension stress

Exclusion Criteria

* medical condition or personal circumstances that will prevent participation and completion of the follow-up visits at 3 weeks, 6 weeks and 3 months post-op
* currently participating in or has participated in (within 30 days prior to inclusion in this study) another clinical trial of an investigational drug, biologic, device, or procedure
* known pre-operative systemic infections, uncontrolled diabetes, or diseases or conditions that are known to interfere with the wound healing process
* Knee alignment deformities greater than 7 degrees varus or valgus
* known prior knee revisions or previous surgeries deemed to compromise the TKA incision exposure
* known medical conditions prohibiting the use of MRI or nickel allergy, sensitivity, or hardware in the region of the knee
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Foundation for Southwest Orthopedic Research

OTHER

Sponsor Role lead

Responsible Party

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Southwest Orthopedic Group, LLP

Locations

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Southwest Orthopedic Group, LLP

Houston, Texas, United States

Site Status

The Methodist Hospital

Houston, Texas, United States

Site Status

Countries

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United States

References

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Lionberger DR, Crocker CL, Chen V. Patient specific instrumentation. J Arthroplasty. 2014 Sep;29(9):1699-704. doi: 10.1016/j.arth.2014.03.019. Epub 2014 Mar 28.

Reference Type DERIVED
PMID: 24810539 (View on PubMed)

Other Identifiers

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0509-0060

Identifier Type: -

Identifier Source: org_study_id

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