Frequency and Origin of Dysnatremias in the Emergency Department

NCT ID: NCT01326429

Last Updated: 2015-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2011-10-31

Study Completion Date

2013-03-31

Brief Summary

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Hypo- and hypernatremia are the most frequent electrolyte disorders found in hospitalized patients. The increasing use of diuretics and other medications influencing the water and sodium homeostasis potentially lead to a rise in the prevalence of the electrolyte disorders. Only little data is available on the frequency and the mechanisms leading to hypo-/hypernatremia.

Thus, the investigators aim to A.) determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital and B.) explore the mechanisms leading to the development of dysnatremias by detailed clinical and laboratory examinations.

Detailed Description

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Conditions

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Hyponatremia Hypernatremia

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Hypernatremia

Patients admitted to the emergency department with a serum sodium exceeding 145 mmol/L.

No interventions assigned to this group

Hyponatremia

Patients admitted to the emergency room with a serum sodium below 135 mmol/L.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Serum sodium below 135 mmol/L (i.e. hyponatremia); serum sodium exceeding 145 mmol/L (hypernatremia)

Exclusion Criteria

* Patients below age 18 years; patients declining study participation.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Steering committee of the NCCR

UNKNOWN

Sponsor Role collaborator

Insel Gruppe AG, University Hospital Bern

OTHER

Sponsor Role lead

Responsible Party

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Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern

Principal Investigators

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Gregor Lindner, M.D.

Role: PRINCIPAL_INVESTIGATOR

Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern

Felix J Frey, M.D.

Role: STUDY_CHAIR

Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern

Related Links

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http://nephrologie.insel.ch

Institution homepage

Other Identifiers

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KEK 019/11

Identifier Type: -

Identifier Source: org_study_id

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