Comparison of the Hemostatic Patch to Fibrin Sealant (TachoSil®) in Subjects Undergoing Hepatic Surgery

NCT ID: NCT01324349

Last Updated: 2014-03-03

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-02-28

Study Completion Date

2011-09-30

Brief Summary

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The objective of this study is to evaluate the safety and effectiveness of Covidien's Hemostatic Patch to control bleeding during hepatic surgery. The performance of the Hemostatic Patch will be compared to Control as an adjunct to conventional hemostatic techniques.

Detailed Description

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Conditions

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Liver Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Veriset Hemostatic Patch

Veriset Hemostatic Patch

Group Type EXPERIMENTAL

Veriset Hemostatic Patch

Intervention Type DEVICE

Topical hemostat

Fibrin Sealant (TachoSil®)

Fibrin Sealant (TachoSil®)

Group Type ACTIVE_COMPARATOR

Fibrin Sealant (TachoSil®)

Intervention Type DEVICE

Topical hemostat

Interventions

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Veriset Hemostatic Patch

Topical hemostat

Intervention Type DEVICE

Fibrin Sealant (TachoSil®)

Topical hemostat

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Scheduled for non-emergent, hepatic surgery
* Presence of an appropriate target bleeding site (TBS) as defined by the protocol

Exclusion Criteria

* Subject will be undergoing a laparoscopic hepatic procedure where the Hemostatic Patch will be delivered and applied through a trocar
* In subjects with documented history of cirrhosis, subject has uncorrected platelet count \<60,000 per mm³ as determined by laboratory tests performed immediately prior to surgery
* Subject has severe coagulopathy defined as INR \> 2.0
* Subject has Total Bilirubin \>2.5mg/dL
* Subject has an active local infection at the Target Bleeding Site
* Study procedure involves a liver transplant recipient
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medtronic - MITG

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Amy Pollack, MD

Role: STUDY_DIRECTOR

Medtronic - MITG

Locations

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Innsbruck, , Austria

Site Status

Ghent, , Belgium

Site Status

Leuven, , Belgium

Site Status

Hanover, , Germany

Site Status

Heidelberg, , Germany

Site Status

München, , Germany

Site Status

Countries

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Austria Belgium Germany

Other Identifiers

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COVEULV0032

Identifier Type: -

Identifier Source: org_study_id

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