InSeal Vascular Closure Device Clinical Study Protocol

NCT ID: NCT01896401

Last Updated: 2016-02-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

33 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-02-29

Study Completion Date

2015-08-31

Brief Summary

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The InSeal vascular closure device (VCD)is assessed as percutaneous closure of artery access sites for quick hemostasis and ambulation in patients who have undergone large bore endovascular catheterization procedures.

The study hypothesis is that the VCD is safe and efficaient in achieving hemostasis in the study population.

Detailed Description

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Conditions

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Percutaneous Closure of Artery Access Sites

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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InSeal's Vascular Closure Device

Use of the experimental VCD to close the access site of the artery

Group Type EXPERIMENTAL

InSeal's Vascular Closure Device

Intervention Type DEVICE

Interventions

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InSeal's Vascular Closure Device

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Candidate for large bore catheterization procedure (such as TAVI, aortic endograft repair) using a CE approved 18Fr access sheath.
* Subject age is at least 18 years
* Patient has signed most recent approved version of the Informed Consent
* Existence of an additional arterial access port is required in instances where an occluding balloon is planned to be used as a safety precaution.

Exclusion Criteria

* Women Of Child Bearing Potential (WOCBP)
* Legally non-competent patients
* Patient participating in another clinical study at the time of the InSeal VCD study
* Prior target artery closure with a vascular closure device having intravascular component (such as Angio-Seal) 30 days prior to catheterization
* Subjects with known coagulopathy, preexisting hematoma, arteriovenous fistula, or pseudoaneurysm at the vessel access site prior to artery closure
* Patients that do not tolerate aspirin and clopidogrel anticoagulation treatment
* Prior vascular surgery or vascular graft in region of access site
* Significant calcification, atherosclerotic disease, or stent within 1.5 cm of the puncture site that may interfere with the operation of the experimental device
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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InSeal Medical Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Cardio Vascular Centrum Frankfurt

Frankfurt, , Germany

Site Status

Countries

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Germany

Other Identifiers

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13-14-003

Identifier Type: -

Identifier Source: org_study_id

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