To Investigate the Prevalence of Children Asthma in China

NCT ID: NCT01319292

Last Updated: 2014-08-04

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 20000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2011-04-30
• Study Completion Date: 2014-04-30

Brief Summary

Asthma is the most common chronic respiratory disease in children and has much effect on their life and study, which leads to huge economic burden and pressure to the whole families. Some children will develop into adult patients so that asthma can be the life-long vigorous trouble. In recent years, the prevalence rate of children asthma is increasingly going up worldwide. The prevalence rate in last 12 months reported in USA, United Kingdom, Australia, New Zealand was between 12% to 30%.

Center for Asthma Prevention and Education of Capital Institute of Pediatrics investigated the national asthma prevalence in 900 thousands children in 27 provinces and cities, which average rate was 0.11% to 2.03% in 1990. In 2000, we investigated it again in 31 provinces(43 cities) and the average national children asthma prevalence rate was 1.97%(0.25% to 4.63%) which was much higher than that in 1990.

Detailed Description

1. Objectives

1. To investigate the national children(0-14 years old)asthma prevalence;

2. To compare the prevalence rate between that in 1990 and 2000;

3. To analyse the asthma manifestations including the ages, seasons, causes, trigger and hereditary factors and their impact on the asthma patients, families and society;

4. To identify the risk factors by questionnaires in case-control research.

2. Study Design / Clinical Plan

1. The screening stage: to distinguish suspected asthma from the children age from 0 to 14 years old.

2. To obtain identified asthma from the suspected asthma.

3. To evaluate the prevalence and severe degree of 0 to 14-year-old children asthma and gain the main risk factors by case-control research.

Conditions

Asthma

Study Design

• Observational Model Type: ECOLOGIC_OR_COMMUNITY
• Study Time Perspective: PROSPECTIVE

Study Groups

Asthma children

children with asthma symptoms through screening

No interventions assigned to this group

normal children

children without symptoms of asthma

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• children age from 0 to 14 years

Exclusion Criteria

• none

• Maximum Eligible Age: 14 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Merck Sharp & Dohme LLC

INDUSTRY

Sponsor Role: collaborator

Capital Institute of Pediatrics, China

OTHER

Sponsor Role: lead

Responsible Party

Chen Yuzhi

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

YuZhi Chen, professor

Role: STUDY_CHAIR

Capital Institute of Pediatrics, China

Other Identifiers

MISP38877

Identifier Type: -

Identifier Source: org_study_id