Clinical Study on Chinese Children's Asthma Action Plan

NCT ID: NCT03435822

Last Updated: 2018-03-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

400 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-03-22

Study Completion Date

2019-06-30

Brief Summary

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This study is a multi-center randomized controlled trial of children with asthma. The objective of the study is to assess the efficacy of China Children Asthma Action Plan (CCAAP), which is the first asthma action plan for children with asthma in China, in asthma management.

Detailed Description

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Asthma is the most common chronic illness of childhood. Asthma action plans have been recommended internationally for more than 20 years by the Global Initiative for Asthma and have been shown to improve asthma-related outcomes. The first asthma action plan for children with asthma in China, which is termed China Children Asthma Action Plan(CCAAP), as well as a mobile phone-based asthma self management application(APP), were developed recently.

The objective of the study is to assess the efficacy of CCAAP in asthma management.

The study is a multi-center prospective case-controlled study.The enrollment period is 3 months. Patients who is in 6-14 years of age will be randomized recruited into two groups: the asthma action plan group and the conventional group. Patients in asthma action plan group will receive written CCAAP and mobile phone-based asthma self-management APP (Youran Respiratory) which includes an electronic asthma action plan, peak expiratory flow monitor system and Peak Expiratory Flow Meter. Patients in conventional management group will write down the symptoms and PEF in asthma diary. The data of the number of asthma episodes, the improvement of FEV1 , the number of unscheduled medical visits, the score of children's quality of life, the questionnaire of asthma knowledge, ACT / C-ACT score, the absent days of parental work, the absent days of children study, and the cost of health economics will be collected regularly in a year with the interval of 3 months to assess the efficacy of CCAAP in asthma management. The study will recruit 200 cases for each group from ten children's hospitals. The study will be completed in a year.

Conditions

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Asthma in Children

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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asthma action plan management group

Patients in this group will be provided both written asthma action plan and mobile-based APP to remind them take medicine regularly and direct them what to do when asthma get worse.

Group Type OTHER

asthma action plan management group

Intervention Type OTHER

Patients will follow the directions in asthma action plan when their asthma get worse.

conventional management group

Patients in this group will be provided conventional management method with prescriptions and asthma diaries.

Group Type OTHER

conventional management group

Intervention Type OTHER

Patients will follow the directions in conventional strategy when their asthma get worse.

Interventions

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asthma action plan management group

Patients will follow the directions in asthma action plan when their asthma get worse.

Intervention Type OTHER

conventional management group

Patients will follow the directions in conventional strategy when their asthma get worse.

Intervention Type OTHER

Other Intervention Names

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conventional management group

Eligibility Criteria

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Inclusion Criteria

* did not receive control treatment or did not reach well-control;
* can perform spirometry pulmonary function tests;
* parents are skilled in using smartphones and APP apps (Android or IOS).

Exclusion Criteria

* reach the level of asthma control;
* can not use the smartphone APP software;
* can not cooperate the test of peak expiratory flow;
* did not treatment coexist respiratory disease effectively (such as sinusitis, obstructive sleep apnea-hypopnea syndrome, etc.);
* combined with other systemic diseases outside the respiratory system (such as leukemia, rheumatoid arthritis, etc.).
* receiving allergen-specific immunotherapy.
* undergoing trial for other medications or instruments.
Minimum Eligible Age

6 Years

Maximum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tian Jing Children's Hospital

UNKNOWN

Sponsor Role collaborator

Capital Institute of Pediatrics, China

OTHER

Sponsor Role collaborator

Peking University Third Hospital

OTHER

Sponsor Role collaborator

Beijing Tsinghua Chang Gung Hospital

OTHER

Sponsor Role collaborator

Tianjin Medical University Second Hospital

OTHER

Sponsor Role collaborator

Peking University Bin Hai Hospital

UNKNOWN

Sponsor Role collaborator

The First Hospital of Qinhuangdao

OTHER_GOV

Sponsor Role collaborator

Tangshan Maternal and Child Health Hospital

OTHER

Sponsor Role collaborator

Children's Hospital of Hebei Province

OTHER

Sponsor Role collaborator

Beijing Children's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Kunling Shen

Chief of China National Clinical Research Center for Respiratory Diseases

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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kunling Shen, MD,PhD

Role: PRINCIPAL_INVESTIGATOR

Beijing Children's Hospital of Capital Medical University

Central Contacts

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Kunling Shen, MD,PhD

Role: CONTACT

59616666 ext. 6308

Other Identifiers

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BCHlung009

Identifier Type: -

Identifier Source: org_study_id

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