The Role of Biomarkers in the Occurrence and Development of Asthma
NCT ID: NCT05768399
Last Updated: 2023-07-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
2 participants
OBSERVATIONAL
2023-07-04
2029-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Asthma group
Children with asthma diagnosed by a respiratory physician
The level of biomarkers in Peripheral blood
All participants will be extracted 5ml peripheral blood into the anticoagulant tube by nurses and the peripheral blood will be detected for biomarkers of asthma. Children with asthma will take pulmonary function, blood test and specific IgE test etc. The lung function test will be performed by professional technicians and the results will be interpreted by specialists. The blood test and specific IgE test will be collected by specialist nurses and the results will be issued by professional inspectors. Children with asthma and their guardians will be asked for filling the questionnaire of Childhood Asthma Control Test (C-ACT). And then the doctor will check and calculate the scores after completion.
Control group
Children without respiratory disease or inflammatory diseases
The level of biomarkers in Peripheral blood
All participants will be extracted 5ml peripheral blood into the anticoagulant tube by nurses and the peripheral blood will be detected for biomarkers of asthma. Children with asthma will take pulmonary function, blood test and specific IgE test etc. The lung function test will be performed by professional technicians and the results will be interpreted by specialists. The blood test and specific IgE test will be collected by specialist nurses and the results will be issued by professional inspectors. Children with asthma and their guardians will be asked for filling the questionnaire of Childhood Asthma Control Test (C-ACT). And then the doctor will check and calculate the scores after completion.
Interventions
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The level of biomarkers in Peripheral blood
All participants will be extracted 5ml peripheral blood into the anticoagulant tube by nurses and the peripheral blood will be detected for biomarkers of asthma. Children with asthma will take pulmonary function, blood test and specific IgE test etc. The lung function test will be performed by professional technicians and the results will be interpreted by specialists. The blood test and specific IgE test will be collected by specialist nurses and the results will be issued by professional inspectors. Children with asthma and their guardians will be asked for filling the questionnaire of Childhood Asthma Control Test (C-ACT). And then the doctor will check and calculate the scores after completion.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Age: 4-12 years old for new diagnosis or recurrent episodes
* Typical clinical manifestations and complete clinical data
* Family members or guardians of children with informed research and signed consent
* All healthy control subjects had no history of lung disease, allergic rhinitis or any other atopic disease
Exclusion Criteria
* Abnormal development of congenital airway and lung tissue
* History of immunosuppressant or glucocorticoid use in the first 4 weeks
* Suffering from other endocrine system and immune system diseases
* Incomplete clinical data or examinations.
4 Years
12 Years
ALL
Yes
Sponsors
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Children's Hospital of Chongqing Medical University
OTHER
Responsible Party
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Fengxia Ding
Reseacher
Locations
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Shaoqing Zhang
Chongqing, Chongqing Municipality, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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File No.2023.225
Identifier Type: -
Identifier Source: org_study_id
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