Identify the Genes Polymorphisms Related to Non-familial Bradyarrhythmia

NCT ID: NCT01310907

Last Updated: 2011-03-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-02-28

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Bradyarrhythmia, including sinus node dysfunction and atrioventricular block, is a major cause necessitating pacemaker implantation. In contrast to familial bradyarrhythmia known as by mutations at particular ion channels, limited information is available for the mechanistic study in non-familial bradyarrhythmia.

Possible gene polymorphisms related to non-familial bradyarrhythmia were studied. Comparison of multi-locus analysis and single-locus analysis will be analyzed between the cases and controls. Functional studies will perform to clarify the results of association study.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Bradyarrhythmia

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

sinus node dysfunction

No interventions assigned to this group

Atrioventricular block

No interventions assigned to this group

control

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* The patients with non-familial bradyarrhythmia

Exclusion Criteria

* Familial bradyarrhythmia Reversible bradyarrhythmia Bradyarrhythmia after open heart surgery and severe organic heart diseases
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

China Medical University, China

OTHER

Sponsor Role collaborator

China Medical University Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

China Medical University Hospital

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Jan-Yow Chen, MD

Role: PRINCIPAL_INVESTIGATOR

China Medical University Hospital

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

China Medical University Hospital

Taichung, Taiwan, Taiwan

Site Status RECRUITING

China Medical University Hospital

Taichung, Taiwan, Taiwan

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Taiwan

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Jan-Yow Chen, MD

Role: CONTACT

+422052121 ext. 2311

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Jan-Yow Chen, MD

Role: primary

+88622052121 ext. 2311

Jan-Yow Chen, MD

Role: primary

+886-4-22052121 ext. 2311

References

Explore related publications, articles, or registry entries linked to this study.

Mangrum JM, DiMarco JP. The evaluation and management of bradycardia. N Engl J Med. 2000 Mar 9;342(10):703-9. doi: 10.1056/NEJM200003093421006. No abstract available.

Reference Type BACKGROUND
PMID: 10706901 (View on PubMed)

Related Links

Access external resources that provide additional context or updates about the study.

http://www.hrsonline.org/

Heart Rhythm Society

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

DMR99-IRB-315

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.