Neuro-urological Outcome After Spinal Cord Injury

NCT ID: NCT01297660

Last Updated: 2016-12-16

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 55 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-01-31
• Study Completion Date: 2010-09-30

Brief Summary

Most patients with spinal cord injury suffer from bladder dysfunction which may - especially in the long-term - impair renal function. Improved treatment during the last decades improved life expectancy and quality of life. This study evaluates the bladder function in the long-term after spinal cord injury.

Detailed Description

Bladder dysfunction is a common consequence of spinal cord injury and depends on the completeness and the level of the lesion. Patients with suprasacral injury usually suffer from neurogenic detrusor overactivity mostly combined with detrusor sphincter dyssynergia. Without adequate treatment, this adverse combination puts the upper urinary tract at risk due to high intravesical pressure often causing vesico-ureteral reflux. Based on improved therapeutic options in the last decades, life expectancy and quality of life constantly increased in spinal cord injury patients. The investigators aim to evaluate the bladder function in the long-term after spinal cord injury.

Conditions

Urinary Bladder Neurogenic Dysfunction

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: RETROSPECTIVE

Study Groups

patients with SCI for at least 5 years

Ages Eligibility: minimum 18 years Genders Eligibility: female and male

Video-urodynamic examination

Intervention Type: OTHER

Interventions

Video-urodynamic examination

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Spinal cord injury for at least 5 years
• Neurogenic lower urinary tract dysfunction
• Written informed consent

Exclusion Criteria

• Lower urinary tract dysfunction due to other causes than spinal cord injury

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Balgrist University Hospital

OTHER

Sponsor Role: lead

Responsible Party

Thomas Kessler

PD Dr. med.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Jens Wöllner, Dr. med.

Role: PRINCIPAL_INVESTIGATOR

Balgrist University Hospital

Locations

Spinal Cord Injury Center & Research, University of Zürich, Balgrist University Hospital

Zurich, Canton of Zurich, Switzerland

Countries

Switzerland

Other Identifiers

KEK-2010-0207/01

Identifier Type: -

Identifier Source: org_study_id