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Neuro-urological Outcome After Spinal Cord Injury

NCT ID: NCT01297660

Last Updated: 2016-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

55 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-31

Study Completion Date

2010-09-30

Brief Summary

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Most patients with spinal cord injury suffer from bladder dysfunction which may - especially in the long-term - impair renal function. Improved treatment during the last decades improved life expectancy and quality of life. This study evaluates the bladder function in the long-term after spinal cord injury.

Detailed Description

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Bladder dysfunction is a common consequence of spinal cord injury and depends on the completeness and the level of the lesion. Patients with suprasacral injury usually suffer from neurogenic detrusor overactivity mostly combined with detrusor sphincter dyssynergia. Without adequate treatment, this adverse combination puts the upper urinary tract at risk due to high intravesical pressure often causing vesico-ureteral reflux. Based on improved therapeutic options in the last decades, life expectancy and quality of life constantly increased in spinal cord injury patients. The investigators aim to evaluate the bladder function in the long-term after spinal cord injury.

Conditions

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Urinary Bladder Neurogenic Dysfunction

Keywords

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neurogenic detrusor overactivity detrusor sphincter dyssynergia compliance video urodynamic spinal cord injury

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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patients with SCI for at least 5 years

Ages Eligibility: minimum 18 years Genders Eligibility: female and male

Video-urodynamic examination

Intervention Type OTHER

Interventions

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Video-urodynamic examination

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Spinal cord injury for at least 5 years
* Neurogenic lower urinary tract dysfunction
* Written informed consent

Exclusion Criteria

* Lower urinary tract dysfunction due to other causes than spinal cord injury
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Balgrist University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Thomas Kessler

PD Dr. med.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jens Wöllner, Dr. med.

Role: PRINCIPAL_INVESTIGATOR

Balgrist University Hospital

Locations

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Spinal Cord Injury Center & Research, University of Zürich, Balgrist University Hospital

Zurich, Canton of Zurich, Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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KEK-2010-0207/01

Identifier Type: -

Identifier Source: org_study_id