Impact of Genetic Polymorphisms on Dental Implant Loss

NCT ID: NCT01274442

Last Updated: 2022-12-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

13 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-06-01

Study Completion Date

2013-08-05

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Patients that may participate in this case-control study underwent dental implant surgery in the University Hospital in Ghent in 2004-2007.

According to one of our recent papers based on this patient group, 34/461 patients lost one or more implants. The goal is to invite these 34 patients, to update the anamnesis, to perform a brief clinical oral examination and to have a blood sample. The latter is necessary to identify relevant genetic polymorphisms of the patient that are associated with implant loss. Among the remaining patients that did not lose implants, another 34 'controls' will be invited for the same examinations.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Patients Treated by Means of 1 or More Dental Implants

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

dental implant

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

CONTROL: no dental implants lost

Group of patients who received an implant during a dental implant surgery in the University Hospital in Ghent in 2004-2007, who did not lose their implants.

Group Type ACTIVE_COMPARATOR

anamnesis

Intervention Type OTHER

To update the anamnesis.

oral examination

Intervention Type PROCEDURE

A brief clinical oral examination will be performed.

Blood sample

Intervention Type PROCEDURE

A blood sample will be taken to identify relevant genetic polymorphisms.

CASE: patients lost one or more implants

Group of patients who received an implant during a dental implant surgery in the University Hospital in Ghent in 2004-2007, but who lost one or more implants.

Group Type EXPERIMENTAL

anamnesis

Intervention Type OTHER

To update the anamnesis.

oral examination

Intervention Type PROCEDURE

A brief clinical oral examination will be performed.

Blood sample

Intervention Type PROCEDURE

A blood sample will be taken to identify relevant genetic polymorphisms.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

anamnesis

To update the anamnesis.

Intervention Type OTHER

oral examination

A brief clinical oral examination will be performed.

Intervention Type PROCEDURE

Blood sample

A blood sample will be taken to identify relevant genetic polymorphisms.

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Dental implant surgery in the University Hospital in Ghent in 2004-2007.
* Case: dental implant loss
* Control: no dental implant loss

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University Hospital, Ghent

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Hugo De Bruyn, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Ghent

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University Hospital Ghent

Ghent, , Belgium

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Belgium

Related Links

Access external resources that provide additional context or updates about the study.

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2010/771

Identifier Type: -

Identifier Source: org_study_id