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Swine Flu (Influenza A H1N1) Follow on Vaccine Study

NCT01239537 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 560

Last updated 2017-12-08

No results posted yet for this study

Summary

In 2009 the World Health Organization (WHO) declared the Influenza A H1N1 (swine 'flu) outbreak the first global pandemic of this century. It is thought to have been responsible for 16,226 deaths globally as of 21st February 2010. The investigators know from previous influenza outbreaks that the number of cases also tends to increase during the winter season of the years after a pandemic. There is concern that last year's pandemic influenza strain will return this winter and it has, therefore, been included in WHO's recommendations for seasonal influenza vaccine combinations.

This study will assess the duration of the immune response to the H1N1 influenza vaccines given last year, and how children will respond to this year's seasonal trivalent influenza vaccine (which includes the H1N1 strain). Participating children would receive one dose of a licensed seasonal influenza vaccine and blood tests would be taken before and after vaccination.

Conditions

  • Influenza

Interventions

DRUG

Seasonal Flu vaccine

1 dose of seasonal trivalent flu vaccine (Fluarix)

Sponsors & Collaborators

  • University of Oxford

    lead OTHER

Principal Investigators

  • Andrew Pollard, MRCP, PhD · Oxford Vaccine Group, University of Oxford

  • Liz Miller, FRCPath, DSc · Public Health England

  • Paul Heath, FRCPCH · St George's Vaccine Institute

  • Adam Finn, PhD, FRCPCH · Bristol Children's Vaccine Centre

  • Saul Faust, MRCPCH, PhD · University of Southampton Wellcome Trust Clinical Research Facility

  • Matthew Snape, FRCPCH, MD · Oxford Vaccine Group

  • Richard Tomlinson · Royal Devon and Exeter NHS Foundation Trust

Eligibility

Min Age
17 Months
Max Age
14 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-11-30
Primary Completion
2010-12-31
Completion
2010-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01239537 on ClinicalTrials.gov