Scoring System for Inhalation Injury

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

108 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-11-30

Study Completion Date

2019-09-29

Brief Summary

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The goal of this multicenter study is to develop a standardized scoring system for inhalation injury that can be used both to quantify and predict injury severity inhalation injury in adults over 18 years of age. A model will be developed based on clinical, radiographic, bronchoscopic, and biochemical parameters that will predict the severity of inhalation injury with greater than 80% predictive accuracy

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Detailed Description

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The goal of this multicenter study is to develop a standardized scoring system for inhalation injury that can be used both to quantify and predict injury severity inhalation injury in adults over 18 years of age. A model will be developed based on clinical, radiographic, bronchoscopic, and biochemical parameters that will predict the severity of inhalation injury with greater than 80% predictive accuracy

Conditions

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Inhalation Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Intubated within 24hrs of admission

All patients that are admitted to a participating burn center and intubated within 24 hours

Standard of Care

Intervention Type OTHER

bronchoscopy with collection of bronchioalveolar lavage specimen, blood samples, High-Resolution spiral computed tomography(CT)

Interventions

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Standard of Care

bronchoscopy with collection of bronchioalveolar lavage specimen, blood samples, High-Resolution spiral computed tomography(CT)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Injury consistent with inhalation of smoke or products of combustion
* Requires intubation within 24 hours of injury
* Meets one of the following 4 criteria

1. history of closed space injury
2. carbonaceous sputum
3. elevated carboxyhemoglobin
4. dx of inhalation injury is considered likely by investigator