The Effect of Pregabalin and Dexamethasone on Acute and Chronic Pain After Lumbar Spinal Surgery
NCT ID: NCT01168531
Last Updated: 2011-08-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
108 participants
INTERVENTIONAL
2009-12-31
2011-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
SUPPORTIVE_CARE
DOUBLE
Study Groups
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placebo arm
placebo
vitamin B complex formula
pregabalin arm
Pregabalin
pregabalin: 300 mg/day, po, from operative day until third postoperative day.
dexamethasone with pregabalin arm
dexamethasone
Dexamethasone 16 mg, intravenous, before induction of anesthesia
Interventions
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Pregabalin
pregabalin: 300 mg/day, po, from operative day until third postoperative day.
dexamethasone
Dexamethasone 16 mg, intravenous, before induction of anesthesia
placebo
vitamin B complex formula
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* alcohol and/or drug abuse
* treatment with antacids or antidepressants
* a history of diabetes or epilepsy
* a daily intake of analgesics or an intake of any analgesic within 24 h before surgery
* treatment with systemic glucocorticoids within 4 weeks before surgery
* known impaired hepatic and renal function.
20 Years
70 Years
ALL
Yes
Sponsors
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Yonsei University
OTHER
Responsible Party
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Department of Anesthesiology & Pain Medicine, Severance Hospital
Locations
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Severance Hospital
Seoul, , South Korea
Countries
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Other Identifiers
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4-2009-0506
Identifier Type: -
Identifier Source: org_study_id
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