Trial Comparing Treatment With SInergy™ System to Conservative Treatment for Chronic Sacroiliac Joint Pain

NCT ID: NCT01158092

Last Updated: 2013-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

5 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-07-31

Brief Summary

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The purpose of this study is to evaluate the effectiveness of cooled radiofrequency denervation of the sacroiliac region using the SInergy System compared to conservative treatment in the treatment of sacroiliac joint pain.

Detailed Description

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Conditions

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Chronic Sacroiliac Joint Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Treatment with SInergy™ System

Lateral branch denervation using the SInergy™ System

Group Type ACTIVE_COMPARATOR

Treatment with SInergy™ System

Intervention Type DEVICE

Lateral branch denervation using the SInergy™ System

Conservative Treatment

Treatment with physical therapy, chiropractic care, and medication

Group Type ACTIVE_COMPARATOR

Conservative Treatment

Intervention Type OTHER

Treatment with physical therapy, chiropractic care, and medication

Interventions

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Treatment with SInergy™ System

Lateral branch denervation using the SInergy™ System

Intervention Type DEVICE

Conservative Treatment

Treatment with physical therapy, chiropractic care, and medication

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Predominantly axial pain below the L5 vertebrae
* \>75% pain relief from 2 separate lateral branch blocks done on different days (followed by return to baseline pain)
* Chronic axial pain lasting for longer than six months: 3 day average VAS between 4 and 8.
* Age greater than 18 years.
* Failed to achieve adequate improvement with comprehensive non-operative treatments, including but not limited to: activity alteration, non-steroidal anti-inflammatory, physical and/or manual therapy, and fluoroscopically guided steroid injections in and around the area of pathology.
* All other possible sources of low back pain have been ruled out, including but not limited to: the intervertebral discs, bone fracture, the zygapophyseal joints, the hip joint, symptomatic spondylolisthesis, tumor and other regional soft tissue structures (this is done by physical exam, medical history, and MRI/CT/X-ray as required)

Exclusion Criteria

* Beck Depression Score \>20 or irreversible psychological barriers to recovery
* Spinal pathology that may impede recovery such as spina bifida occulta, spondylolisthesis at L5/S1, or scoliosis.
* Moderate or severe foraminal or central canal stenosis
* Systemic infection or localized infection at anticipated introducer entry site.
* Concomitant cervical or thoracic pain greater than 2/10 on a VAS
* Uncontrolled or acute illness
* Chronic severe conditions such as rheumatoid/inflammatory arthritis
* Pregnancy
* Active radicular pain
* Immunosuppression (eg. AIDS, cancer, diabetes, surgery \<3 months ago)
* Worker's compensation, injury litigation, or disability remuneration
* Allergy to injectants or medications used in procedure
* High narcotics use (\>30 mg hydrocodone or equivalent)
* Patients who smoke. Termination for at least 6 months and no smoking during follow up period are acceptable with caution.
* Body Mass Index greater than 29.9 (obese).
* Subject unwilling to consent to the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Baylis Medical Company

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Edgar L Ross, M.D.

Role: PRINCIPAL_INVESTIGATOR

Brigham and Women's Hospital

Locations

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Brigham and Women's Hospital Pain Trials Center

Chestnut Hill, Massachusetts, United States

Site Status

Countries

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United States

Other Identifiers

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BMC-SI-CIP-002

Identifier Type: -

Identifier Source: org_study_id

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