The Effect of Masking on Subjective Results During Daily Disposable Contact Lens Studies

NCT ID: NCT01155726

Last Updated: 2012-07-10

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

134 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-05-31

Study Completion Date

2011-02-28

Brief Summary

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The purpose of this study is to explore the effect of masking on subjective ratings for two daily disposable contact lenses.

Detailed Description

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Conditions

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Myopia Hyperopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Nelfilcon A, Masked, Unmasked

Nelfilcon A worn in adaptation phase (bilaterally, 30 days). Period 1: 1DAVM and DACP (masked) worn contralaterally in random assignment for 3 days. Period 2: 1DAVM and DACP (unmasked) worn contralaterally, same assignment, 3 days. All products worn in a daily wear, daily disposable mode.

Group Type ACTIVE_COMPARATOR

Nelfilcon A contact lens

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses inserted and removed by participant.

Nelfilcon A contact lens with comfort additive (DACP), unmasked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens with comfort additive for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses and removed inserted by participant.

Nelfilcon A contact lens with comfort additive (DACP), masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and packaging not visible to participant. Lenses inserted and removed by the investigator.

Etafilcon A contact lens with comfort additive (1DAVM), unmasked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens with comfort additive for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses inserted and removed by participant.

Etafilcon A contact lens with comfort additive (1DAVM), masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and packaging not visible to participant. Lenses inserted and removed by the investigator.

Nelfilcon A, Masked, Partially Masked

Nelfilcon A worn in adaptation phase (bilaterally, 30 days). Period 1: 1DAVM and DACP (masked) worn contralaterally in random assignment for 3 days. Period 2: 1DAVM and DACP (partially masked) worn contralaterally, same assignment, 3 days. All products worn in a daily wear, daily disposable mode.

Group Type ACTIVE_COMPARATOR

Nelfilcon A contact lens

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses inserted and removed by participant.

Nelfilcon A contact lens with comfort additive (DACP), masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and packaging not visible to participant. Lenses inserted and removed by the investigator.

Nelfilcon A contact lens with comfort additive (DACP), partially masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Lens name and manufacturer on blister pack label concealed from participant. Lenses inserted and removed by the participant.

Etafilcon A contact lens with comfort additive (1DAVM), masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and packaging not visible to participant. Lenses inserted and removed by the investigator.

Etafilcon A contact lens with comfort additive (1DAVM), partially masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Lens name and manufacturer on blister pack label concealed from participant. Lenses inserted and removed by the participant.

Etafilcon A, Masked, Unmasked

Etafilcon A worn in adaptation phase (bilaterally, 30 days). Period 1: 1DAVM and DACP (masked) worn contralaterally in random assignment for 3 days. Period 2: 1DAVM and DACP (unmasked) worn contralaterally, same assignment, 3 days. All products worn in a daily wear, daily disposable mode.

Group Type ACTIVE_COMPARATOR

Nelfilcon A contact lens with comfort additive (DACP), unmasked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens with comfort additive for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses and removed inserted by participant.

Nelfilcon A contact lens with comfort additive (DACP), masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and packaging not visible to participant. Lenses inserted and removed by the investigator.

Etafilcon A contact lens

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses inserted and removed by participant.

Etafilcon A contact lens with comfort additive (1DAVM), unmasked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens with comfort additive for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses inserted and removed by participant.

Etafilcon A contact lens with comfort additive (1DAVM), masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and packaging not visible to participant. Lenses inserted and removed by the investigator.

Etafilcon A, Masked, Partially Masked

Etafilcon A worn in adaptation phase (bilaterally, 30 days). Period 1: 1DAVM and DACP (masked) worn contralaterally in random assignment for 3 days. Period 2: 1DAVM and DACP (partially masked) worn contralaterally, same assignment, 3 days. All products worn in a daily wear, daily disposable mode.

Group Type ACTIVE_COMPARATOR

Nelfilcon A contact lens with comfort additive (DACP), masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and packaging not visible to participant. Lenses inserted and removed by the investigator.

Nelfilcon A contact lens with comfort additive (DACP), partially masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Lens name and manufacturer on blister pack label concealed from participant. Lenses inserted and removed by the participant.

Etafilcon A contact lens

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses inserted and removed by participant.

Etafilcon A contact lens with comfort additive (1DAVM), masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and packaging not visible to participant. Lenses inserted and removed by the investigator.

Etafilcon A contact lens with comfort additive (1DAVM), partially masked

Intervention Type DEVICE

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Lens name and manufacturer on blister pack label concealed from participant. Lenses inserted and removed by the participant.

Interventions

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Nelfilcon A contact lens

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses inserted and removed by participant.

Intervention Type DEVICE

Nelfilcon A contact lens with comfort additive (DACP), unmasked

Commercially marketed, soft, hydrogel contact lens with comfort additive for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses and removed inserted by participant.

Intervention Type DEVICE

Nelfilcon A contact lens with comfort additive (DACP), masked

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and packaging not visible to participant. Lenses inserted and removed by the investigator.

Intervention Type DEVICE

Nelfilcon A contact lens with comfort additive (DACP), partially masked

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Lens name and manufacturer on blister pack label concealed from participant. Lenses inserted and removed by the participant.

Intervention Type DEVICE

Etafilcon A contact lens

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses inserted and removed by participant.

Intervention Type DEVICE

Etafilcon A contact lens with comfort additive (1DAVM), unmasked

Commercially marketed, soft, hydrogel contact lens with comfort additive for daily wear, daily disposable use. Blister pack label and lens packaging visible to participant. Lenses inserted and removed by participant.

Intervention Type DEVICE

Etafilcon A contact lens with comfort additive (1DAVM), masked

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Blister pack label and packaging not visible to participant. Lenses inserted and removed by the investigator.

Intervention Type DEVICE

Etafilcon A contact lens with comfort additive (1DAVM), partially masked

Commercially marketed, soft, hydrogel contact lens for daily wear, daily disposable use. Lens name and manufacturer on blister pack label concealed from participant. Lenses inserted and removed by the participant.

Intervention Type DEVICE

Other Intervention Names

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Focus DAILIES® DAILIES® AquaComfort Plus® DAILIES® AquaComfort Plus® DAILIES® AquaComfort Plus® 1-DAY ACUVUE® 1-DAY ACUVUE® MOIST® 1-DAY ACUVUE® MOIST® 1-DAY ACUVUE® MOIST®

Eligibility Criteria

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Inclusion Criteria

* 17 years of age or older.
* Ocular exam within 2 years.
* Currently wearing soft contact lenses on a daily wear basis.
* Contact lens prescription between +6.00D and -10.00D.

Exclusion Criteria

* Any ocular disease.
* Use of systemic or ocular medications that may affect ocular health.
* Unable to achieve an acceptable fit with the study lenses.
* Anisometropia \>1.00D or astigmatism \>0.75D.
Minimum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CIBA VISION

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Centre for Contact Lens Research: University of Waterloo

Waterloo, Ontario, Canada

Site Status

Countries

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Canada

Other Identifiers

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P-371-C-101

Identifier Type: -

Identifier Source: org_study_id