Clinical Comparison of Silicone Hydrogel and HEMA-based Daily Disposable Contact Lenses

NCT ID: NCT01362907

Last Updated: 2012-08-03

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-05-31

Study Completion Date

2011-06-30

Brief Summary

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The purpose of this trial was to compare the performance of an investigational daily disposable contact lens to a commercially available daily disposable contact lens.

Detailed Description

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Conditions

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Myopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Delefilcon A / etafilcon A

Delefilcon A contact lenses worn first, with etafilcon A contact lenses worn second. Both products worn bilaterally on a daily wear, daily disposable basis for one week each.

Group Type OTHER

Delefilcon A contact lens

Intervention Type DEVICE

Investigational, silicone hydrogel, single vision, soft contact lens for daily disposable wear

Etafilcon A contact lens

Intervention Type DEVICE

Commercially marketed, HEMA-based, single vision, soft contact lens for daily disposable wear

Etafilcon A / delefilcon A

Etafilcon A contact lenses worn first, with delefilcon A contact lenses worn second. Both products worn bilaterally on a daily wear, daily disposable basis for one week each.

Group Type OTHER

Delefilcon A contact lens

Intervention Type DEVICE

Investigational, silicone hydrogel, single vision, soft contact lens for daily disposable wear

Etafilcon A contact lens

Intervention Type DEVICE

Commercially marketed, HEMA-based, single vision, soft contact lens for daily disposable wear

Interventions

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Delefilcon A contact lens

Investigational, silicone hydrogel, single vision, soft contact lens for daily disposable wear

Intervention Type DEVICE

Etafilcon A contact lens

Commercially marketed, HEMA-based, single vision, soft contact lens for daily disposable wear

Intervention Type DEVICE

Other Intervention Names

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DAILIES® Total1® 1-DAY ACUVUE® MOIST™

Eligibility Criteria

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Inclusion Criteria

* Normal eyes with no use of ocular medications.
* Be of legal age of consent and sign Informed Consent document. If under legal age of consent, legally authorized representative must sign Informed Consent document and subject must sign Assent document.
* Willing and able to wear spherical contact lenses for protocol-specified timeframe within the available range of powers (-1.00 D to -6.00D in 0.25D steps).
* Visual acuity with study lenses 20/25 or better.
* Cylinder less than or equal to 0.75 D.
* Currently wearing daily disposable lenses.

Exclusion Criteria

* Anterior segment infection, inflammation, or abnormality.
* Any active anterior segment ocular disease that would contraindicate contact lens wear.
* Any use of systemic medications for which contact lens wear could be contraindicated as determined by the investigator.
* History of refractive surgery or irregular cornea.
* Eye injury within twelve weeks immediately prior to enrollment for this trial.
* Currently enrolled in any clinical trial.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CIBA VISION

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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P-347-C-013

Identifier Type: -

Identifier Source: org_study_id