Product Performance of a New Silicone Hydrogel Contact Lens

NCT ID: NCT04901897

Last Updated: 2021-07-08

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

805 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-07-31

Study Completion Date

2019-10-09

Brief Summary

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The objective of this study is to evaluate the product performance of kalifilcon A, compared to the Johnson \& Johnson Acuvue Oasys® 1-Day with HydraLuxe™ (senofilcon A) daily disposable contact lens and Alcon DAILIES TOTAL1® (delefilcon A) daily disposable contact lenses when worn by current soft contact lens wearers on a daily disposable wear basis.

Detailed Description

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Conditions

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Myopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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kalifilcon A

kalifilcon A daily disposable contact lens

Group Type EXPERIMENTAL

kalifilcon A

Intervention Type DEVICE

kalifilcon A daily disposable contact lens

delefilcon A

DAILIES TOTAL1® (delefilcon A) daily disposable contact lenses

Group Type ACTIVE_COMPARATOR

delefilcon A

Intervention Type DEVICE

DAILIES TOTAL1® (delefilcon A) daily disposable contact lenses

senofilcon A

Acuvue Oasys® 1-Day with HydraLuxe™ (senofilcon A) daily disposable contact lens

Group Type ACTIVE_COMPARATOR

senofilcon A

Intervention Type DEVICE

Acuvue Oasys® 1-Day with HydraLuxe™ (senofilcon A) daily disposable contact lens

Interventions

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kalifilcon A

kalifilcon A daily disposable contact lens

Intervention Type DEVICE

delefilcon A

DAILIES TOTAL1® (delefilcon A) daily disposable contact lenses

Intervention Type DEVICE

senofilcon A

Acuvue Oasys® 1-Day with HydraLuxe™ (senofilcon A) daily disposable contact lens

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* 18 to 40 years old on the date the ICF is signed and have capacity to provide voluntary informed consent.
* myopic and require lens correction from -0.50 to -6.00 Diopter (D) with 0.25 D steps, in each eye.
* correctable through spherocylindrical refraction and with soft spherical contact lenses to 32 letters (0.3 logarithm of the minimum angle of resolution \[logMAR\]) or better (2 meters distance, high-contrast chart) in each eye.
* free of any anterior segment disorders.
* adapted soft contact lens wearers and willing to wear their study lenses for at least 8 hours per day on a daily disposable wear basis for approximately 2 weeks.
* access to internet connection and personal email to send/receive emails.
* habitually wear either Alcon's Air Optix Aqua, Air Optix with HydraGlyde, Air Optix Night \& Day, Bausch + Lomb's PureVision 2, Bausch + Lomb ULTRA, CooperVision's Biofinity, Johnson \& Johnson Acuvue Oasys® with HydraClear™, or Acuvue Vita soft contact lenses.

Exclusion Criteria

* participating in any drug or device clinical investigation within 2 weeks prior to entry into this study (Screening/Dispensing Visit) and/or during the period of study participation.
* have worn gas permeable (GP) contact lenses within the last 30 days or who have worn polymethylmethacrylate (PMMA) lenses within the last three months.
* have any systemic or ocular disease currently affecting ocular health in the Investigator's opinion may have an effect on ocular health during the course of the study.
* using any systemic, topical or topical ocular medications that will in the Investigator's opinion, affect ocular physiology or lens performance.currently wear daily disposable, monovision, multifocal, or toric contact lenses.
* refractive astigmatism of greater than 0.75 D in either eye.
* anisometropia (spherical equivalent) of greater than 2.00 D.
* amblyopic.
* have had any corneal surgery (e.g., refractive surgery).
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bausch & Lomb Incorporated

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Robert Steffen

Role: STUDY_DIRECTOR

Bausch & Lomb Incorporated

Locations

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Bausch Site 433

Birmingham, Alabama, United States

Site Status

Bausch Site 431

Scottsdale, Arizona, United States

Site Status

Bausch Site 406

Azusa, California, United States

Site Status

Bausch Site 430

Los Angeles, California, United States

Site Status

Bausch Site 419

San Diego, California, United States

Site Status

Bausch Site 435

San Francisco, California, United States

Site Status

Bausch Site 432

Sunnyvale, California, United States

Site Status

Bausch Site 409

Torrance, California, United States

Site Status

Bausch Site 416

Denver, Colorado, United States

Site Status

Bausch Site 415

Jacksonville, Florida, United States

Site Status

Bausch Site 434

Jacksonville, Florida, United States

Site Status

Bausch Site 405

Sarasota, Florida, United States

Site Status

Bausch Site 412

Decatur, Georgia, United States

Site Status

Bausch Site 437

Honolulu, Hawaii, United States

Site Status

Bausch Site 401

‘Aiea, Hawaii, United States

Site Status

Bausch Site 414

Leavenworth, Kansas, United States

Site Status

Bausch Site 413

Portland, Maine, United States

Site Status

Bausch Site 421

Sterling Heights, Michigan, United States

Site Status

Bausch Site 429

Edina, Minnesota, United States

Site Status

Bausch Site 422

Raytown, Missouri, United States

Site Status

Bausch Site 407

St Louis, Missouri, United States

Site Status

Bausch Site 418

Warrensburg, Missouri, United States

Site Status

Bausch Site 424

Jamestown, New York, United States

Site Status

Bausch Site 403

Vestal, New York, United States

Site Status

Bausch Site 417

Raleigh, North Carolina, United States

Site Status

Bausch Site 411

Fargo, North Dakota, United States

Site Status

Bausch Site 423

Miamisburg, Ohio, United States

Site Status

Bausch Site 425

West Chester, Ohio, United States

Site Status

Bausch Site 428

Grants Pass, Oregon, United States

Site Status

Bausch Site 420

State College, Pennsylvania, United States

Site Status

Bausch Site 427

Warwick, Rhode Island, United States

Site Status

Bausch 410

Brentwood, Tennessee, United States

Site Status

Bausch Site 408

Memphis, Tennessee, United States

Site Status

Bausch Site 404

Nashville, Tennessee, United States

Site Status

Bausch Site 426

League City, Texas, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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893

Identifier Type: -

Identifier Source: org_study_id

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