Role of Cord Blood Hormones and Epinephrine in the Development of Transient Tachypnea of the Newborn

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-09-30

Study Completion Date

2009-10-31

Brief Summary

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In this prospective, cross-sectional study, the aim was to investigate the possible role of cord stress hormones; adrenocorticotropic hormone (ACTH), cortisol, epinephrine, sT3, sT4, and thyroid-stimulating hormone (TSH) in the development of Transient Tachypnea of the Newborn (TTN), via their modulatory effect on epithelial sodium channels and Na-K-ATPase.

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Detailed Description

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Conditions

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Wet Lung

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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C/S delivered, wet lung

No interventions assigned to this group

C/S delivered, healthy infants

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Gestation age \> 34 weeks
* C/S delivered infants
* Parental consent form signed

Exclusion Criteria

* Gestation age \< 34 weeks
* Maternal conditions that compromised fetal well-being (hypertensive disorder, diabetes, chorioamnionitis)
* Intrauterine growth retardation
* Congenital malformations
* Absence of parental consent

Minimum Eligible Age

34 Weeks

Maximum Eligible Age

40 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes