The Effect of DHEA on Markers of Ovarian Reserve in Women With Diminished Ovarian Reserve

NCT ID: NCT01129830

Last Updated: 2014-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

EARLY_PHASE1

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-31

Study Completion Date

2014-09-30

Brief Summary

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This prospective study evaluates the effect of DHEA supplementation on markers of ovarian reserve in women with diminished ovarian reserve.

Detailed Description

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Ovarian reserve markers, such as FSH, estradiol, AMH, ovarian volume and antral follicle counts will be monitored on DHEA supplementation in a prospective fashion.

Conditions

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Infertility

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Dehydroepiandrosterone

infertile women with low anti mullerian hormone levels

Group Type OTHER

dehydroepiandrosterone

Intervention Type DIETARY_SUPPLEMENT

DHEA supplementation 25 mg tid for 3 months

Interventions

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dehydroepiandrosterone

DHEA supplementation 25 mg tid for 3 months

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* infertile women with diminished ovarian reserve

Exclusion Criteria

* women \> 45
Minimum Eligible Age

21 Years

Maximum Eligible Age

44 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Virginia Center for Reproductive Medicine

OTHER

Sponsor Role lead

Responsible Party

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Fady I. Sharara, M.D

Medical Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Fady I Sharara, M.D

Role: PRINCIPAL_INVESTIGATOR

Virginia Center for Reproductive Medicine

Locations

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Virginia Center for Reproductive Medicine

Reston, Virginia, United States

Site Status

Countries

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United States

References

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Barad D, Brill H, Gleicher N. Update on the use of dehydroepiandrosterone supplementation among women with diminished ovarian function. J Assist Reprod Genet. 2007 Dec;24(12):629-34. doi: 10.1007/s10815-007-9178-x. Epub 2007 Dec 11.

Reference Type BACKGROUND
PMID: 18071895 (View on PubMed)

Other Identifiers

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VCRM 3

Identifier Type: -

Identifier Source: org_study_id

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