Suture Fixation System Versus Tendonous Reconstruction in Carpometacarpal (CMC) Arthroplasty

NCT ID: NCT01121874

Last Updated: 2018-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

53 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-04-12

Study Completion Date

2012-07-25

Brief Summary

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Thumb carpometacarpal (CMC) arthritis affect 1 in 4 females and 1 in 12 males. Patients who fail to respond to conservative treatment may benefit from surgery; however, controversy exists over the most effective surgical technique. A popular technique, ligament reconstruction with tendon interposition (LRTI) involves a trapeziectomy, followed by reconstruction of the palmar oblique ligament using a harvested flexor tendon from the wrist.

We believe that use of a suture fixation system to reconstruct the palmar oblique ligament, instead of harvesting a wrist tendon, may provide a superior repair. The objective of this study is to compare functional outcome measurements among patients who receive CMC arthroplasty using a suture fixation system (investigational group) to those who receive LRTI surgery (control group). We hypothesize that patients in the investigational group will demonstrate superior functionality, compared to patients in the control group.

Detailed Description

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Conditions

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Thumb Carpometacarpal Arthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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LRTI

These patients will undergo ligament reconstruction with tendon interposition (LRTI) surgery. They will serve as a control group, against which to compare the investigational surgical technique.

Group Type ACTIVE_COMPARATOR

Ligament Reconstruction with Tendon Interposition (LRTI)

Intervention Type PROCEDURE

commonly performed CMC arthroplasty technique, consisting of a trapeziectomy, followed by palmar oblique ligament reconstruction using a harvested flexor tendon from the wrist.

Suture fixation system

CMC arthroplasty which reconstructs palmar oblique ligament using a suture fixation system.

Group Type EXPERIMENTAL

Ligament reconstruction with suture fixation system

Intervention Type PROCEDURE

CMC arthroplasty consisting of reconstruction of the palmar oblique ligament using a suture fixation system

Suture fixation system + 2 week immobilization

CMC arthroplasty which reconstructs palmar oblique ligament using a suture fixation system, and with a decreased immobilization time from 6 to 2 weeks post-surgery.

Group Type EXPERIMENTAL

Ligament reconstruction with suture fixation system

Intervention Type PROCEDURE

CMC arthroplasty consisting of reconstruction of the palmar oblique ligament using a suture fixation system, with a decreased period of immobilization from 6 weeks to 2 weeks.

Interventions

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Ligament reconstruction with suture fixation system

CMC arthroplasty consisting of reconstruction of the palmar oblique ligament using a suture fixation system

Intervention Type PROCEDURE

Ligament Reconstruction with Tendon Interposition (LRTI)

commonly performed CMC arthroplasty technique, consisting of a trapeziectomy, followed by palmar oblique ligament reconstruction using a harvested flexor tendon from the wrist.

Intervention Type PROCEDURE

Ligament reconstruction with suture fixation system

CMC arthroplasty consisting of reconstruction of the palmar oblique ligament using a suture fixation system, with a decreased period of immobilization from 6 weeks to 2 weeks.

Intervention Type PROCEDURE

Other Intervention Names

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Arthrex Mini TightRope Arthrex Mini TightRope

Eligibility Criteria

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Inclusion Criteria

* Male or female patients aged \>18.
* Eaton Stage III or IV CMC arthritis
* Failure to respond to conservative treatment

Exclusion Criteria

* Previous surgical interventions on that thumb
* Upper extremity neurological dysfunction
* Inability to effectively communicate with the research staff, due to hearing impairment, cognitive impairment, or a language barrier
* Unwilling or unable to provide written informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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J&M Shuler

INDUSTRY

Sponsor Role lead

Responsible Party

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Michael Shuler

Hand and Upper Extremity Specialist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Michael Shuler, MD

Role: PRINCIPAL_INVESTIGATOR

Athens Orthopedic Clinic, PA

Locations

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Athens Orthopedic Clinic

Athens, Georgia, United States

Site Status

Countries

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United States

Other Identifiers

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CMC-101

Identifier Type: -

Identifier Source: org_study_id

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