Cyanoacrylate and Laser and Dentin Sensitivity

NCT ID: NCT01111474

Last Updated: 2020-08-17

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 62 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2008-08-31
• Study Completion Date: 2009-02-28

Brief Summary

This study aimed to evaluate the effectiveness of two treatments for dental hypersensitivity: cyanoacrylate (Super Bonder®) compared with use of low intensity laser treatment (LILT). As the cyanoacrylate is a lower cost treatment, the hypothesis in investigation is if this product is equally effective as the laser treatment.

Detailed Description

The present study included 62 patients (15 male and 47 females, aged 12 to 60 years). The initial cervical dentin hypersensitivity was checked throughout a thermal test (air blast). The 434 teeth included were that with a score ≥5 in a numerical scale rating of pain. Teeth were randomly assigned according quadrants (split mouth design) - 216 were allocated to LILT group and 218 for the Super Bonder® group. Thermal tests with a tetrafluoroethane spray (Endo-Ice®) and air blast were performed and considered as baseline. Pain parameters were recorded using a numerical scale rating with 24 hours, 30, 90 and 180 days after the interventions. Quality of life of the patients was also assessed with the use of OHIP-14 at baseline and after 180 days.

Conditions

Dentin Hypersensitivity; Dentin Sensitivity

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: TRIPLE

Study Groups

Cyanoacrylate

3 applications of cyanoacrylate (48 hours interval)at the cervical region of the sensitive tooth

Group Type: ACTIVE_COMPARATOR

Cyanoacrylate

Intervention Type: OTHER

3 applications of cyanoacrylate (48 hours interval) at the cervical region of the sensitive tooth

Laser

3 Low intensity laser application (48 hour interval). The application of 1Joule/cm\^2 was performed for eight seconds at three points along the dental neck, using the infrared wavelength (795nm)

Group Type: ACTIVE_COMPARATOR

Laser

Intervention Type: RADIATION

This process was conducted three times with an interval of 48 hours between applications, according to laser's manufacturer advice Clean Line Easy Laser - LILT®, Clean Line Easy Laser Doctor Dental Products Industry LTDA, BRA). For dentin hypersensitivity, the application of 1Joule/cm\^2 is recommended for eight seconds at three points along the dental neck, using the infrared wavelength (795nm).

Interventions

Cyanoacrylate

3 applications of cyanoacrylate (48 hours interval) at the cervical region of the sensitive tooth

Intervention Type: OTHER

Laser

This process was conducted three times with an interval of 48 hours between applications, according to laser's manufacturer advice Clean Line Easy Laser - LILT®, Clean Line Easy Laser Doctor Dental Products Industry LTDA, BRA). For dentin hypersensitivity, the application of 1Joule/cm\^2 is recommended for eight seconds at three points along the dental neck, using the infrared wavelength (795nm).

Intervention Type: RADIATION

Other Intervention Names

Superbonder; LILT

Eligibility Criteria

Inclusion Criteria

1. patients should be in good general and dental health;

2. present complaints of dental sensitivity to cold, sweet, acidic foods and brushing;

3. present complaints of pain in teeth located in different quadrants;

4. manifest pain or discomfort upon application of the triple syringe air jet;

5. not be in current use of desensitizing agents.

Exclusion Criteria

1. presence of extensive restorations and carious lesions in the sensitive teeth;

2. undergoing orthodontic treatment;

3. frequent use of analgesics, antidepressants and anti-inflammatory drugs;

4. presence of gingival inflammation;

5. non-consent of patient.

• Minimum Eligible Age: 12 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Federal University of the Valleys of Jequitinhonha and Mucuri

OTHER

Sponsor Role: collaborator

Federal University of São Paulo

OTHER

Sponsor Role: lead

Responsible Party

Olga Flecha

PHD student

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Olga D. Flecha, pHD student

Role: PRINCIPAL_INVESTIGATOR

UNIFESP - Federal University of São Paulo, Brazil

Other Identifiers

odf2008

Identifier Type: -

Identifier Source: org_study_id