Study Comparing CT Scan and Stress Test in Patients With Known Coronary Artery Disease Hospitalized for Chest Pain

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

7 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-04-30

Study Completion Date

2013-12-31

Brief Summary

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The purpose of this study is to determine whether coronary artery CT scanning or nuclear stress testing is better at diagnosing chest pain patients with known coronary artery disease to select appropriate candidates for coronary catheterization and re-vascularization.

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Detailed Description

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Conditions

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Coronary Artery Disease Angina Pectoris Unstable Angina Acute Coronary Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Initial coronary CT angiography

EKG-gated, computed tomography angiography of the coronary arteries during heart rate control

Group Type EXPERIMENTAL

Coronary CT angiography

Intervention Type PROCEDURE

EKG-gated, computed tomography angiography of the coronary arteries during heart rate control

Initial nuclear stress test

Stress radionuclide myocardial perfusion imaging

Group Type ACTIVE_COMPARATOR

Myocardial perfusion imaging

Intervention Type PROCEDURE

Stress radionuclide myocardial perfusion imaging

Interventions

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Coronary CT angiography

EKG-gated, computed tomography angiography of the coronary arteries during heart rate control

Intervention Type PROCEDURE

Myocardial perfusion imaging

Stress radionuclide myocardial perfusion imaging

Intervention Type PROCEDURE

Other Intervention Names

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Coronary CTA Coronary CT CTA of the coronary arteries CT of the coronary arteries CTA CCTA Cardiac CTA Cardiac CT CT Angiography of the coronary arteries Computed tomography angiography of the coronary arteries MPI MPS stress MPI stress MPS radionuclide MPI stress nuclear nuclear stress nuclear stress test nuclear stress testing nuclear cardiology nuclear perfusion imaging nuclear myocardial perfusion imaging myocardial perfusion

Eligibility Criteria

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Inclusion Criteria

* patient admitted for chest pain / pressure or other suggestive symptoms
* patient has known coronary artery disease (with or without prior revascularization)
* patient has clinical need for non-invasive cardiac evaluation

Exclusion Criteria

* evidence of ongoing myocardial infarction or hemodynamic instability
* ischemia on EKG (greater than 1mm ST segment deviation)
* contraindications to CT scanning with iodinated intravenous contrast (including allergies, asthma and renal dysfunction)
* heart rhythm precluding EKG gating
* pregnancy

Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No