Dengue Seroprevalence Study in Blood Donors in the French West Indies

NCT ID: NCT01104740

Last Updated: 2021-08-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

817 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-05-31

Study Completion Date

2012-05-31

Brief Summary

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Dengue is an infectious disease most prevalent in the world. This disease is endemic in the Caribbean, with an increase in seasonal rains. Several outbreaks have been observed in recent years, in 2001, 2005 and 2007, during which further particularly virulent serotypes have emerged. The clinical expression of dengue fever is variable, ranging from no symptoms to a classical form with fever, and even of severe or lethal bleeding. With the possible existence of silent forms of the disease, there are no data identifying the current level of protection of the population in Martinique / Guadeloupe.

Detailed Description

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1. Principal objective:

To estimate the prevalence of the specific antibodies of the dengue (IgG) in blood donors in the French West Indies.
2. Secondary objective:

To specify the serotypic specificity of the anti-dengue antibodies detected during the study.

Conditions

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Blood Donors Dengue

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Biological sample collection

Blood (serum) sample collection

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Eligible for blood donation following the French legislation,
* Resident in Martinique /Guadeloupe for at least one year
* Consent signed

Exclusion Criteria

* Not Eligible for blood donation following the French legislation,
* Not Resident in Martinique / Guadeloupe for at least one year
* Consent not signed
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sanofi Pasteur, a Sanofi Company

INDUSTRY

Sponsor Role collaborator

Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV

Sponsor Role collaborator

Clinique Antilles-Guyane

OTHER

Sponsor Role collaborator

Etablissement Français du Sang, Martinique

OTHER

Sponsor Role lead

Responsible Party

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RICHARD

Directrice EFS Martinique

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Pascale RICHARD, MD

Role: PRINCIPAL_INVESTIGATOR

French Blood Establishment of Martinique

Locations

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French Blood Establishment of Guadeloupe

Pointe-à-Pitre, , Guadeloupe

Site Status

French Blood Establishment of Martinique

Fort-de-France, , Martinique

Site Status

Countries

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Guadeloupe Martinique

Other Identifiers

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2010-A00385-34

Identifier Type: OTHER

Identifier Source: secondary_id

10/B/01

Identifier Type: -

Identifier Source: org_study_id

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