Autologous Serum Skin Test and Serum IL-18 Levels in Chronic Idiopathic Urticaria and Respiratory Allergic Diseases

NCT ID: NCT01091402

Last Updated: 2010-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Study Classification

OBSERVATIONAL

Study Start Date

2009-01-31

Brief Summary

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One of the proposed mechanisms in CU is autoimmunity. It was shown by a positive response to autologous serum skin test (ASST)in almost half of chronic urticaria (CU) patients. IL-18 also play a role in autoimmune disorders. The investigators aim was to investigate the relationship of ASST and IL-18 in CU and respiratory allergic diseases.

Detailed Description

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Conditions

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Urticaria Respiratory Allergic Diseases

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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chronic urticaria

autologous serum skin test, serum IL-18

Intervention Type PROCEDURE

asthma

autologous serum skin test, serum IL-18

Intervention Type PROCEDURE

seasonal allergic rhinitis

autologous serum skin test, serum IL-18

Intervention Type PROCEDURE

normal controls

autologous serum skin test, serum IL-18

Intervention Type PROCEDURE

Interventions

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autologous serum skin test, serum IL-18

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* adult patients
* chronic urticaria patients
* stable asthma patients
* allergic rhinitis patients with sensitized to pollens
* normal controls without atopic and skin disease.

Exclusion Criteria

* unwillingness to the study
* other dermatological problems that could affect the skin test
* use of antihistamine drugs
Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Eskisehir Osmangazi University

OTHER

Sponsor Role lead

Locations

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Eskisehir Osmangazi University

Eskişehir, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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1

Identifier Type: -

Identifier Source: org_study_id

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