Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis

NCT ID: NCT00952835

Last Updated: 2013-06-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-07-31

Study Completion Date

2014-12-31

Brief Summary

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In this study will be consecutive enrolled children with asthma (classified according to GINA guidelines) and rhinitis (classified by ARIA guidelines); the investigators will research clinical personal and parental history regarding allergic diseases, exposition to passive smoking and interpretate hematochemical parameters markers of atopy. Skin Prick Tests will be performed. In this study the investigators will evaluate lung function parameters (spirometry with bronchial reversibility test and exercise induced bronchoconstriction, oscillometry, respiratory plethysmography, etc.), airway inflammatory indices such as exhaled nitric oxide at different flows, exhaled and nasal temperature, nasal cytology.

The aim of the study will be to evaluate possible correlation between these different parameters and clinical status of the patients.

Detailed Description

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Each patients will be evaluated by spirometry and then he will undergo exercise challenge in order to evaluate exercise-induced bronchoconstriction as a marker of asthma control. The test of the challenge will be correlate with childhood Asthma control test score,levels of control (GINA classification)and the different markers of airway inflammation and atopy.

Conditions

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Asthma Rhinitis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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asthma and rhinitis control

regular treatment

Intervention Type OTHER

regular treatment

Interventions

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regular treatment

regular treatment

Intervention Type OTHER

Other Intervention Names

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asthma treatment

Eligibility Criteria

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Inclusion Criteria

* patient with asthma and rhinitis

Exclusion Criteria

* age \<5 years
* chronic respiratory diseases
Minimum Eligible Age

5 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Azienda Ospedaliera Universitaria Policlinico

OTHER

Sponsor Role collaborator

Universita di Verona

OTHER

Sponsor Role lead

Responsible Party

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Boner Attilio

full professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Attilio Boner, MD

Role: PRINCIPAL_INVESTIGATOR

Universita di Verona

Locations

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Pediatric department University of Verona

Verona, Verona, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Attilio Boner, MD

Role: CONTACT

--390458124615

Facility Contacts

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Attilio Boner, MD

Role: primary

--390458124615

References

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Chinellato I, Piazza M, Peroni D, Sandri M, Chiorazzo F, Boner AL, Piacentini G. Bronchial and alveolar nitric oxide in exercise-induced bronchoconstriction in asthmatic children. Clin Exp Allergy. 2012 Aug;42(8):1190-6. doi: 10.1111/j.1365-2222.2012.03973.x.

Reference Type DERIVED
PMID: 22805466 (View on PubMed)

Peroni DG, Cattazzo E, Chinellato I, Piazza M, Tezza G, Boner AL, Piacentini GL. Nasal mucosa temperature as a marker of disease in children with allergic rhinitis. Am J Rhinol Allergy. 2012 Jul-Aug;26(4):e115-8. doi: 10.2500/ajra.2012.26.3803.

Reference Type DERIVED
PMID: 22801008 (View on PubMed)

Other Identifiers

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AOV-1716

Identifier Type: -

Identifier Source: org_study_id

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