Fractional Exhaled Nitric Oxide (FeNO) Result Prediction Factors in Children With Allergic Diseases

NCT ID: NCT00815984

Last Updated: 2010-02-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-01-31

Study Completion Date

2010-01-31

Brief Summary

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In about 800 children with allergic diseases (asthma, allergic rhinitis, atopic dermatitis) the investigators will retrospectively and cross-sectionally analyze the influence/correlation of diagnosis, treatment methods, allergy status (skin prick test results), lung function tests results on/with the concentration of nitric oxide in exhaled breath.

Detailed Description

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In about 800 children with allergic diseases from our Outpatient Clinic (asthma, allergic rhinitis, atopic dermatitis) we will retrospectively and cross-sectionally analyse the influence/correlation of diagnosis, treatment methods, allergy status (skin prick test results), lung function tests results on/with the concentration of nitric oxide in exhaled breath.

Conditions

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Asthma Allergic Rhinitis Atopic Dermatitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Schoolchildren with asthma.

Schoolchildren with asthma.

measurements of lung function tests

Intervention Type PROCEDURE

Measurement of the concentration of FeNO , measurement of spirometry, plethysmography, exercise challenge test (ECT -spirometric), bronchial obstruction reversibility pharmacological test

Interventions

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measurements of lung function tests

Measurement of the concentration of FeNO , measurement of spirometry, plethysmography, exercise challenge test (ECT -spirometric), bronchial obstruction reversibility pharmacological test

Intervention Type PROCEDURE

Other Intervention Names

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NO analyzer- Sievers 280i analyzer Spirometry and Plethysmography - Jaeger Exercise provocation test treadmill- Kettler

Eligibility Criteria

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Inclusion Criteria

* Children with asthma (allergic), and/or allergic rhinitis and/or atopic dermatitis

Exclusion Criteria

* Other chronic diseases
* Asthma exacerbation
* Pregnancy
Minimum Eligible Age

5 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Lodz

OTHER

Sponsor Role lead

Responsible Party

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Department of Pediatrics and Allergy, N. Copernicus Hospital, Lodz, Poland

Principal Investigators

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Iwona Stelmach, MD PhD Prof

Role: STUDY_CHAIR

Department of Pediatrics and Allergy, N. Copernicus Hospital, Lodz, Poland

Tomasz Grzelewski, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Pediatrics and Allergy, N. Copernicus Hospital, Lodz, Poland

Locations

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Department of Pediatrics and Allergy, N. Copernicus Hospital

Lodz, , Poland

Site Status

Countries

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Poland

References

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Grzelewski T, Majak P, Jerzynska J, Stelmach W, Stelmach R, Janas A, Grzelewska A, Witkowski K, Makandjou-Ola E, Stelmach I. The interpretation of exhaled nitric oxide values in children with asthma depends on the degree of bronchoconstriction and the levels of asthma severity. Respir Care. 2014 Sep;59(9):1404-11. doi: 10.4187/respcare.02889. Epub 2013 Dec 31.

Reference Type DERIVED
PMID: 24381190 (View on PubMed)

Other Identifiers

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RNN/135/08/KE

Identifier Type: -

Identifier Source: org_study_id

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