Chest Wall Kinematics and Respiratory Muscle Action During Supine Breathing in Individuals With and Without Spinal Cord Injury
NCT ID: NCT01084512
Last Updated: 2010-03-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
50 participants
OBSERVATIONAL
2005-07-31
2008-07-31
Brief Summary
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Design: cross sectional repeated-measure with age matched control group. Setting: Motion Analysis Laboratory Participants: Seven tetraplegic and five paraplegic subjects and twelve age matched healthy controls were recruited.
Intervention: Not applicable.
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Detailed Description
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Results: Ttetraplegic individuals had smallerΔVUT andΔVLT than those of control subjects(P\< .006 and .006, respectively). Furthermore, the ΔVr of AB was greater than those of UT and LT( P\< .006, .006, respectively), PVAB was smaller than PVLT ( P\< .006), PPVUT was greater than PPVLT and PPVAB ( P\< .008, .008, respectively ). The paraplegic subjects had smallerΔVLT than that of control subjects ( P\< .006 ). ΔVr of UT was greater than that of LT, and both PVUT and PVAB were greater than PVLT ( P\< .006 and .006, respectively). However, the paraplegic subjects preferred to all three compartments to achieve the maximal inspiration, like control group. In control group, onlyΔVAB was comparable with other compartments. ΔVr of UT was greater than LT, and PVUT was greater than PVLT and PVAB ( P\<.006 and .006, respectively). For the RMS EMG, it demonstrated that average RMS EMG of two muscles in both tetraplegic and paraplegic group were greater than that in control group (P\< .017 and .017, respectively).
Conclusion: The results applied the three-compartment model of chest wall to investigate the breathing pattern by OEP in individuals with and without SCI during inspiration of vital capacity breathing in supine posture. There were some interesting findings that (1) the tetraplegic subjects used AB contributed most volume changes, they can expand the AB more easily, and the UT took the responsibility to performed the final adjust during the inspiration; (2) the paraplegic subjects used UT contributed the most volume changes, they expanded the both UT and AB more easily, and all three compartment moved together during the inspiration; (3) the control subjects used UT to increase the most volume changes, they can expand UT more than the others, and all three compartments moved together during the inspiration phase, (4) the results of RMS EMG showed that the central neural drive in both tetraplegic and paraplegic subjects were greater than control group.
Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Healthy group
control subjects
No interventions assigned to this group
Paraplegic group
Paraplegic subjects
No interventions assigned to this group
Tetraplegic group
tetraplegic subjects
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* (2) post-injury duration at least 0.5 year;
* (3) male subject due to high incidence rate in Taiwan20and the necessity of total exposure of the chest wall during the data collection.
Exclusion Criteria
* (2) with any respiratory disease and musculoskeletal problem that interfered with the experimental protocol;
* (3) having infections during the data collection period.
20 Years
60 Years
MALE
Yes
Sponsors
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National Science and Technology Council, Taiwan
OTHER_GOV
National Taiwan University Hospital
OTHER
Responsible Party
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National Taiwan University
Locations
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School and graduate institute of physical therapy
Taipei, Taiwan, Taiwan
Countries
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Other Identifiers
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9461701293
Identifier Type: -
Identifier Source: org_study_id
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