Effect of Turmeric on Pruritus in Hemodialysis Patients

NCT ID: NCT01037595

Last Updated: 2013-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2010-12-31

Brief Summary

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The purpose of this study is to see whether turmeric can be effective in treatment of pruritus in hemodialysis patients.

Detailed Description

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pruritus is a common in hemodialysis patients and many treatment recommended for it . as turmeric has anti-inflammatory , anti-cytokine and anti-oxidant effect it may effective in treatment of uremic pruritus. thus we compared turmeric with placebo in this study

Conditions

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End Stage Renal Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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turmeric

turmeric 500 mg tid orally for 8 weeks

Group Type EXPERIMENTAL

turmeric

Intervention Type DRUG

turmeric 500 md tid orally for 8 weeks

turmeric

Intervention Type DRUG

500 mg tid orally for 8 weeks

plasebo

placebo tid orally for 8 weeks

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DRUG

placebo 3 time orally for 8 weeks

Interventions

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turmeric

turmeric 500 md tid orally for 8 weeks

Intervention Type DRUG

placebo

placebo 3 time orally for 8 weeks

Intervention Type DRUG

turmeric

500 mg tid orally for 8 weeks

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Hemodialysis for more than 3 months
* More than 18 years old
* Pruritus

Exclusion Criteria

* Use other treatment for pruritus
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Shiraz University of Medical Sciences

OTHER

Sponsor Role lead

Responsible Party

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Maryam Pakfetrat

associated professor of shiraz Shiraz University of Medical Sciences

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Shiraz University Hemodialysis Center

Shiraz, Fars, Iran

Site Status

Countries

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Iran

References

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Hercz D, Jiang SH, Webster AC. Interventions for itch in people with advanced chronic kidney disease. Cochrane Database Syst Rev. 2020 Dec 7;12(12):CD011393. doi: 10.1002/14651858.CD011393.pub2.

Reference Type DERIVED
PMID: 33283264 (View on PubMed)

Other Identifiers

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3441

Identifier Type: -

Identifier Source: org_study_id

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