Symptomatic Treatment of Common Cold Symptoms

NCT ID: NCT01033526

Last Updated: 2009-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

388 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-10-31

Study Completion Date

2007-06-30

Brief Summary

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A two-arm, multicenter, randomized, double-blind, single dose placebo-controlled parallel groups study evaluating efficacy and tolerability of 800 mg Acetylsalicylic Acid (Aspirina C) in adult patients with a common cold during a two hour in patient phase; and a follow-up period of five days of home treatment as required.

Detailed Description

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Conditions

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Common Cold

Keywords

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Symptomatic treatment of Common Cold symptoms

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Arm 2

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

1-2 tablets matching Placebo as needed every 4-6 hours over a maximum of 5 days

Arm 1

Group Type EXPERIMENTAL

Aspirin (Acetylsalicylic acid, BAYE4465)

Intervention Type DRUG

1-2 tablets Acetylsalicylic Acid 400 mg (in combination with Ascorbic Acid 240 mg) as needed every 4-6 hours over a maximum of 5 days

Interventions

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Aspirin (Acetylsalicylic acid, BAYE4465)

1-2 tablets Acetylsalicylic Acid 400 mg (in combination with Ascorbic Acid 240 mg) as needed every 4-6 hours over a maximum of 5 days

Intervention Type DRUG

Placebo

1-2 tablets matching Placebo as needed every 4-6 hours over a maximum of 5 days

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 65 years
* Onset of cold symptoms within 48 hours before screening
* Objective symptoms of common cold
* Subjective symptoms of common cold

Exclusion Criteria

* Pregnancy or lactation period
* Active peptic ulcer
* Hemorrhagic diathesis
* History of chronic or recurrent ulcer disease or history of gastro-intestinal bleeding
* Hypersensitivity to acetylsalicylic acid, to paracetamol, to any other component of the study medication, to anti-inflammatory or antirheumatic drugs, to other allergens
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Bayer Consumer Care Inc.

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Borgo di Terzo, Bergamo, Italy

Site Status

Brembate, Bergamo, Italy

Site Status

Calusco d'Adda, Bergamo, Italy

Site Status

Capriate San Gervasio, Bergamo, Italy

Site Status

Caravaggio, Bergamo, Italy

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Casazza, Bergamo, Italy

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Cologno al Serio, Bergamo, Italy

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Covo, Bergamo, Italy

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Dalmine, Bergamo, Italy

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Mozzanica, Bergamo, Italy

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Ponte San Pietro, Bergamo, Italy

Site Status

Seriate, Bergamo, Italy

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Verdello, Bergamo, Italy

Site Status

Vertova, Bergamo, Italy

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Villa d'Adda, Bergamo, Italy

Site Status

Angera, Varese, Italy

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Carnago, Varese, Italy

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Cavaria, Varese, Italy

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Comerio, Varese, Italy

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Cunardo, Varese, Italy

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Fagnano Olona, Varese, Italy

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Induno Olona, Varese, Italy

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Sesto Calende, Varese, Italy

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Solbiate Olona, Varese, Italy

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Varese, Varese, Italy

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Vedano Olona, Varese, Italy

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Vergiate, Varese, Italy

Site Status

Albano Sant'Alessandro, , Italy

Site Status

Countries

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Italy

Other Identifiers

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EudraCT: 2004-004683-71

Identifier Type: -

Identifier Source: secondary_id

11756

Identifier Type: -

Identifier Source: org_study_id